Right-to-left ventricular end diastolic diameter ratio in severe sepsis and septic shock

Meghan M. Cirulis; Jessica H. Huston; Partha Sardar; Promporn Suksaranjit; Brent D. Wilson; Nathan D. Hatton; Theodore G. Liou; John J. Ryan

doi:10.1016/j.jcrc.2018.09.025

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Right-to-left ventricular end diastolic diameter ratio in severe sepsis and septic shock

Journal article

Peer reviewed

Right-to-left ventricular end diastolic diameter ratio in severe sepsis and septic shock

Meghan M. Cirulis, Jessica H. Huston, Partha Sardar, Promporn Suksaranjit, Brent D. Wilson, Nathan D. Hatton, Theodore G. Liou and John J. Ryan

Journal of critical care, Vol.48, pp.307-310

12/2018

DOI: 10.1016/j.jcrc.2018.09.025

PMCID: PMC7971347

PMID: 30273910

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Abstract

The ratio of right ventricular end-diastolic diameter (EDD) to left ventricular EDD (RV/LV) is a measure predictive of right ventricular failure. We hypothesized that an increase in RV/LV would be associated with poor prognosis in severe sepsis and septic shock. This is a retrospective chart review of patients with severe sepsis and septic shock admitted to a medical intensive care unit (ICU) at a single tertiary care hospital. Patients were identified by ICD-9 codes: 995.92 for severe sepsis and 785.52 for septic shock; and had to have an echocardiogram within 48 h of ICU admission. Increased RV/LV was defined as RV/LV ≥ 0.9. Left and right-sided chamber dimensions were measured according to American Society of Echocardiography guidelines. We included 146 consecutive ICU patients admitted with septic shock (72) or severe sepsis (74). There was no significant difference in ICU mortality in patients with RV/LV ≥ 0.9 versus RV/LV < 0.9 (p = .49). An increased RV/LV does not predict mortality in severe sepsis or septic shock. •An increase in the right to left ventricle end-diastolic diameter ratio is not predictive of increased mortality in severe sepsis and septic shock.•RV end diastolic diameter is not an independent predictor of mortality this population•Other echocardiographic predictors of mortality in sepsis should be explored

Echocardiography

Heart ventricles

Intensive care unit

Prognosis

Sepsis

Septic shock

Details

Title: Subtitle: Right-to-left ventricular end diastolic diameter ratio in severe sepsis and septic shock
Creators: Meghan M. Cirulis - University of Utah
Jessica H. Huston - University of Utah
Partha Sardar - University of Utah
Promporn Suksaranjit - University of Utah
Brent D. Wilson - University of Utah
Nathan D. Hatton - University of Utah
Theodore G. Liou - University of Utah
John J. Ryan - University of Utah
Resource Type: Journal article
Publication Details: Journal of critical care, Vol.48, pp.307-310
DOI: 10.1016/j.jcrc.2018.09.025
PMID: 30273910
PMCID: PMC7971347
NLM abbreviation: J Crit Care
ISSN: 0883-9441
eISSN: 1557-8615
Publisher: Elsevier Inc
Grant note: name: NHLBI/NIH, award: R01 HL125520; DOI: 10.13039/100000897, name: US Cystic Fibrosis Foundation, award: LIOU13A0, LIOU14Y4, CC132-16AD, LIOU14Y0, LIOU14P0; name: Ben B. And Iris M. Margolis Family Foundation of Utah; name: Claudia Ruth Goodrich Stevens Endowment Fund; DOI: 10.13039/100006483, name: Abbvie; DOI: 10.13039/100005564, name: Gilead; name: Nivalis; DOI: 10.13039/100004336, name: Novartis; name: Proteostasis, Inc.; DOI: 10.13039/100015511, name: Savara; DOI: 10.13039/100011022, name: Vertex
Language: English
Date published: 12/2018
Academic Unit: Cardiovascular Medicine; Internal Medicine
Record Identifier: 9984359836402771

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