Journal article
Risk and Survival of Patients with Head and Neck Cutaneous Melanoma: National Perspective
Oncology, Vol.93(1), pp.18-28
2017
DOI: 10.1159/000458530
PMID: 28423377
Abstract
Head and neck cutaneous melanoma represents a distinct entity of skin cancer. We aim to examine management and survival of patients with head and neck cutaneous melanoma.
A retrospective cohort study utilizing the National Cancer Database, 2004-2012.
A total of 20,322 (21.2%) head and neck melanomas and 75,547 (78.8%) melanomas of other sites were included. The median follow-up time of head and neck melanoma was 41.6 months (interquartile range: 22.9-68.2 months). Patients with melanoma of the head and neck were more likely to be ≥65 years old, male, and/or white (p < 0.001 each). Positive surgical margin was more prevalent in head and neck melanoma [OR: 2.19, 95% CI: (2.03, 2.37)], and was associated with a lower survival [HR: 1.41, 95% CI: (1.28, 1.57)]. High positive lymph node ratio was associated with a lower survival [HR: 2.00, 95% CI: (1.13, 3.57)]. Adjuvant immunotherapy was associated with an improved survival [HR: 0.67, 95% CI: (0.57, 0.80)].
Head and neck cutaneous melanoma is associated with certain demographics. Surgical margin status, lymph node ratio, and immunotherapy are independently associated with overall survival.
Details
- Title: Subtitle
- Risk and Survival of Patients with Head and Neck Cutaneous Melanoma: National Perspective
- Creators
- Zaid Al-Qurayshi - University of Iowa Hospitals and ClinicsMohamed HassanSudesh SrivastavSteven SperryNitin PagedarJohn HamnerEmad Kandil
- Resource Type
- Journal article
- Publication Details
- Oncology, Vol.93(1), pp.18-28
- DOI
- 10.1159/000458530
- PMID
- 28423377
- ISSN
- 0030-2414
- eISSN
- 1423-0232
- Language
- English
- Date published
- 2017
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984312248002771
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