Risk factors associated with repair of orbital and lateral skull defects

Nicholas A Serrano; Gilean N Trenité; Bevan Yueh; D Gregory Farwell; Neal D Futran; Eduardo Méndez

doi:10.1001/archfacial.2011.1301

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Journal article

Risk factors associated with repair of orbital and lateral skull defects

Nicholas A Serrano, Gilean N Trenité, Bevan Yueh, D Gregory Farwell, Neal D Futran and Eduardo Méndez

Archives of facial plastic surgery, Vol.14(2), pp.97-103

03/01/2012

DOI: 10.1001/archfacial.2011.1301

PMID: 22183060

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Abstract

To explore the complications and associated risks factors after orbital exenteration and lateral skull base defect repair. Patients who had undergone a reconstruction of their orbital cavity and lateral skull base defects were selected from our departmental database. The outcome of interest was postoperative complications. The risks factors were defined as age, sex, history of radiation therapy, and intracranial involvement (with and without dural involvement). Information was collected on the type of reconstruction used after the orbital cavity repair. The χ(2) test and logistic regression were used to analyze associations between postoperative complications and the various risks factors. Of the 32 identified patients, 19 had intracranial involvement (9 with dural involvement). Twenty-four patients underwent reconstruction with free tissue transfer in the same setting. Reconstruction with free tissue transfer was significantly associated with fewer major postoperative complications (P < .053). There was a trend toward more complications with a history of radiation therapy or intracranial involvement. Reconstruction of the orbital cavity and lateral skull base can be challenging, especially if there is a history of radiation therapy and intracranial involvement. Free tissue transfer is a safe and effective method for reconstruction of such defects.

Adult

Age Distribution

Aged

Databases, Factual

Esthetics

Female

Graft Rejection

Humans

Incidence

Logistic Models

Male

Middle Aged

Multivariate Analysis

Neoplasm Invasiveness - pathology

Orbital Neoplasms - pathology

Orbital Neoplasms - surgery

Postoperative Complications - diagnosis

Postoperative Complications - epidemiology

Postoperative Complications - surgery

Reconstructive Surgical Procedures - adverse effects

Reconstructive Surgical Procedures - methods

Reoperation

Retrospective Studies

Risk Factors

Sex Distribution

Skull Base Neoplasms - pathology

Skull Base Neoplasms - surgery

Surgical Flaps - blood supply

Surgical Wound Infection - diagnosis

Surgical Wound Infection - epidemiology

Surgical Wound Infection - surgery

Treatment Outcome

Wound Healing - physiology

Details

Title: Subtitle: Risk factors associated with repair of orbital and lateral skull defects
Creators: Nicholas A Serrano - Fred Hutch Cancer Center
Gilean N Trenité
Bevan Yueh
D Gregory Farwell
Neal D Futran
Eduardo Méndez
Resource Type: Journal article
Publication Details: Archives of facial plastic surgery, Vol.14(2), pp.97-103
DOI: 10.1001/archfacial.2011.1301
PMID: 22183060
NLM abbreviation: Arch Facial Plast Surg
ISSN: 1521-2491
eISSN: 1538-3660
Language: English
Date published: 03/01/2012
Academic Unit: Otolaryngology
Record Identifier: 9984966857302771

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