Journal article
Risk factors for erosion of artificial urinary sphincters: a multicenter prospective study
Urology (Ridgewood, N.J.), Vol.84(4), pp.934-939
10/2014
DOI: 10.1016/j.urology.2014.05.043
PMCID: PMC4307589
PMID: 25109562
Abstract
To evaluate the short- to medium-term outcomes after artificial urinary sphincter (AUS) placement from a large, multi-institutional, prospective, follow-up study. We hypothesize that along with radiation, patients with any history of a direct surgery to the urethra will have higher rates of eventual AUS explantation for erosion and/or infection.
A prospective outcome analysis was performed on 386 patients treated with AUS placement from April 2009 to December 2012 at 8 institutions with at least 3 months of follow-up. Charts were analyzed for preoperative risk factors and postoperative complications requiring explantation.
Approximately 50% of patients were considered high risk. High risk was defined as patients having undergone radiation therapy, urethroplasty, multiple treatments for bladder neck contracture or urethral stricture, urethral stent placement, or a history of erosion or infection in a previous AUS. A total of 31 explantations (8.03%) were performed during the follow-up period. Overall explantation rates were higher in those with prior radiation and prior UroLume. Men with prior AUS infection or erosion also had a trend for higher rates of subsequent explantation. Men receiving 3.5-cm cuffs had significantly higher explantation rates than those receiving larger cuffs.
This outcomes study confirms that urethral risk factors, including radiation history, prior AUS erosion, and a history of urethral stent placement, increase the risk of AUS explantation in short-term follow-up.
Details
- Title: Subtitle
- Risk factors for erosion of artificial urinary sphincters: a multicenter prospective study
- Creators
- William O Brant - Department of Surgery, Division of Urology, Center for Reconstructive Urology and Men's Health, University of Utah, Salt Lake City, UT. Electronic address: Dr.w.brant@gmail.comBradley A Erickson - Department of Urology, University of Iowa, Iowa City, IASean P Elliott - Department of Urology, University of Minnesota, Minneapolis, MNChristopher Powell - Department of Urology, University of Kansas Medical Center, Kansas City, KSNejd Alsikafi - Department of Urology, Loyola University, Chicago, ILChristopher McClung - Ohio State University, Columbus, OHJeremy B Myers - Department of Surgery, Division of Urology, Center for Reconstructive Urology and Men's Health, University of Utah, Salt Lake City, UTBryan B Voelzke - Department of Urology, University of Washington, Seattle, WAThomas G Smith III - Scott Department of Urology, Baylor College of Medicine, Houston, TXJoshua A Broghammer - Department of Urology, University of Kansas Medical Center, Kansas City, KS
- Resource Type
- Journal article
- Publication Details
- Urology (Ridgewood, N.J.), Vol.84(4), pp.934-939
- DOI
- 10.1016/j.urology.2014.05.043
- PMID
- 25109562
- PMCID
- PMC4307589
- NLM abbreviation
- Urology
- ISSN
- 0090-4295
- eISSN
- 1527-9995
- Publisher
- United States
- Grant note
- KL2 RR025015 / NCRR NIH HHS KL2 TR000421 / NCATS NIH HHS UL1 TR000423 / NCATS NIH HHS
- Language
- English
- Date published
- 10/2014
- Academic Unit
- Urology
- Record Identifier
- 9984051799502771
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