Journal article
Risk factors for in-stent restenosis after vertebral ostium stenting
Journal of endovascular therapy, Vol.15(2), pp.203-212
04/2008
DOI: 10.1583/07-2175.1
PMID: 18426264
Abstract
To determine whether vascular risk factors, underlying vessel diameter, and/or the type of stent affect restenosis rates for vertebral ostium stents.
A single-center retrospective analysis was conducted of 44 patients (31 men; mean age 61 years, range 32-81) who underwent stenting of 48 ostial lesions in the vertebral arteries between 1999 and 2005. Only patients who underwent angiographic follow-up were included in the analysis. Cox regression analysis was utilized for risk factor association with binary restenosis (> or =50% versus <50%). Stent types and stent categories were compared for differences in binary restenosis rates and lumen gain at follow-up angiography.
Twenty-three (48%) of 48 lesions had > or =50% stenosis at a mean follow-up of 7.7 months. Cigarette smoking was associated with higher binary restenosis rates (p=0.025), while hypertension, diabetes, hyperlipidemia, history of neck radiation, and known coronary artery and/or peripheral vascular disease were not. Reduced binary restenosis rates and improved lumen gain were seen in cobalt chromium balloon-expandable stents compared to non-cobalt chromium stents (p=0.002 and p=0.002, respectively), stainless steel balloon-expandable stents (p=0.005 and p=0.005), and the S670 stent (p=0.069 and p=0.069). The size of stent used was not associated with risk of restenosis (p=0.756).
Cobalt chromium stents were associated with reduced restenosis, while smoking was associated with increased restenosis risk.
Details
- Title: Subtitle
- Risk factors for in-stent restenosis after vertebral ostium stenting
- Creators
- Robert A Taylor - Department of Neurology, University of Minnesota, Minneapolis, Minnesota, USA. rataylor@umn.eduFarhan SiddiqM Fareed K SuriColeman O MartinMinako HayakawaJohn C Chaloupka
- Resource Type
- Journal article
- Publication Details
- Journal of endovascular therapy, Vol.15(2), pp.203-212
- Publisher
- United States
- DOI
- 10.1583/07-2175.1
- PMID
- 18426264
- ISSN
- 1526-6028
- eISSN
- 1545-1550
- Language
- English
- Date published
- 04/2008
- Academic Unit
- Neurology; Radiology
- Record Identifier
- 9984020715002771
Metrics
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