Journal article
Risk factors for long coronavirus disease 2019 (long COVID) among healthcare personnel, Brazil, 2020-2022
Infection control and hospital epidemiology, Vol.44(12), pp.1972-1978
12/2023
DOI: 10.1017/ice.2023.95
PMCID: PMC10755155
PMID: 37272468
Appears in UI Libraries Support Open Access
Abstract
OBJECTIVETo determine risk factors for the development of long coronavirus disease 2019 (COVID-19) in healthcare personnel (HCP). METHODSWe conducted a case-control study among HCP who had confirmed symptomatic COVID-19 working in a Brazilian healthcare system between March 1, 2020, and July 15, 2022. Cases were defined as those having long COVID according to the Centers for Disease Control and Prevention definition. Controls were defined as HCP who had documented COVID-19 but did not develop long COVID. Multiple logistic regression was used to assess the association between exposure variables and long COVID during 180 days of follow-up. RESULTSOf 7,051 HCP diagnosed with COVID-19, 1,933 (27.4%) who developed long COVID were compared to 5,118 (72.6%) who did not. The majority of those with long COVID (51.8%) had 3 or more symptoms. Factors associated with the development of long COVID were female sex (OR, 1.21; 95% CI, 1.05-1.39), age (OR, 1.01; 95% CI, 1.00-1.02), and 2 or more SARS-CoV-2 infections (OR, 1.27; 95% CI, 1.07-1.50). Those infected with the SARS-CoV-2 δ (delta) variant (OR, 0.30; 95% CI, 0.17-0.50) or the SARS-CoV-2 o (omicron) variant (OR, 0.49; 95% CI, 0.30-0.78), and those receiving 4 COVID-19 vaccine doses prior to infection (OR, 0.05; 95% CI, 0.01-0.19) were significantly less likely to develop long COVID. CONCLUSIONSLong COVID can be prevalent among HCP. Acquiring >1 SARS-CoV-2 infection was a major risk factor for long COVID, while maintenance of immunity via vaccination was highly protective.
Details
- Title: Subtitle
- Risk factors for long coronavirus disease 2019 (long COVID) among healthcare personnel, Brazil, 2020-2022
- Creators
- Alexandre R Marra - University of IowaVanderson Souza Sampaio - Instituto de SaúdeMina Cintho Ozahata - Instituto de SaúdeRafael Lopes - Instituto de SaúdeAnderson F Brito - Instituto de SaúdeMarcelo Bragatte - Instituto de SaúdeJorge Kalil - Instituto de SaúdeJoão Luiz Miraglia - Hospital Israelita Albert EinsteinDaniel Tavares Malheiro - Hospital Israelita Albert EinsteinYang Guozhang - Hospital Israelita Albert EinsteinVanessa Damazio Teich - Hospital Israelita Albert EinsteinElivane da Silva VictorJoão Renato Rebello Pinho - Hospital Israelita Albert EinsteinAdriana Cypriano - Hospital Israelita Albert EinsteinLaura Wanderly Vieira - Hospital Israelita Albert EinsteinMiria Polonio - Hospital Israelita Albert EinsteinSolange Miranda de Oliveira - Hospital Israelita Albert EinsteinVictória Catharina Volpe Ricardo - Hospital Israelita Albert EinsteinAline Miho Maezato - Hospital Israelita Albert EinsteinGustavo Yano Callado - Hospital Israelita Albert EinsteinGuilherme de Paula Pinto SchettinoKetti Gleyzer de Oliveira - Hospital Israelita Albert EinsteinRúbia Anita Ferraz Santana - Hospital Israelita Albert EinsteinFernanda de Mello MaltaDeyvid Amgarten - Hospital Israelita Albert EinsteinAna Laura Boechat - Hospital Israelita Albert EinsteinTakaaki Kobayashi - University of IowaEli Perencevich - University of IowaMichael B Edmond - West Virginia UniversityLuiz Vicente Rizzo - Hospital Israelita Albert Einstein
- Resource Type
- Journal article
- Publication Details
- Infection control and hospital epidemiology, Vol.44(12), pp.1972-1978
- DOI
- 10.1017/ice.2023.95
- PMID
- 37272468
- PMCID
- PMC10755155
- NLM abbreviation
- Infect Control Hosp Epidemiol
- eISSN
- 1559-6834
- Publisher
- Cambridge University Press
- Language
- English
- Electronic publication date
- 06/05/2023
- Date published
- 12/2023
- Academic Unit
- Infectious Diseases; Epidemiology; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984426745602771
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