Risk factors for urinary incontinence among women with type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study

Aruna V Sarma; Alka Kanaya; Leroy M Nyberg; John W Kusek; Eric Vittinghoff; Brandy Rutledge; Patricia A Cleary; Patricia Gatcomb; Jeanette S Brown; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group

doi:10.1016/j.urology.2008.11.009

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Risk factors for urinary incontinence among women with type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study

Journal article

Open access

Peer reviewed

Risk factors for urinary incontinence among women with type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study

Aruna V Sarma, Alka Kanaya, Leroy M Nyberg, John W Kusek, Eric Vittinghoff, Brandy Rutledge, Patricia A Cleary, Patricia Gatcomb, Jeanette S Brown and Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group

Urology (Ridgewood, N.J.), Vol.73(6), pp.1203-1209

06/2009

DOI: 10.1016/j.urology.2008.11.009

PMCID: PMC2748226

PMID: 19362350

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Abstract

To determine risk factors for, and long-term effects of, glycemic control on urinary incontinence among women with type 1 diabetes enrolled in the Epidemiology of Diabetes Interventions and Complications study. The Diabetes Control and Complications Trial (1982-1993) cohort follow-up, Epidemiology of Diabetes Interventions and Complications trial, began in 1994. In 2004, the female participants (n = 550) completed a self-administered questionnaire on incontinence. Our primary outcome was weekly or greater incontinence, overall and by type. Multivariate regression models were used to determine independent predictors of weekly urinary incontinence, both overall and by type. Overall, 38% of women reported any incontinence and 17% reported weekly or greater incontinence. An increasing body mass index (odds ratio 1.1, 95% confidence interval 1.1-1.2) was significantly associated with weekly incontinence, overall and by type. Advancing age and >/=2 urinary tract infections in the previous year were associated with weekly urge incontinence (odds ratio 1.4, 95% confidence interval 1.0-2.0 per 5 years, and odds ratio 4.9, 95% confidence interval 1.8-13.5, respectively). Weaker evidence was seen for increased risk with age for overall weekly incontinence (22% per 5 years, P = .06) and stress incontinence (21% per 5 years, P = .08). Urinary incontinence is common among women with type 1 diabetes and the risk factors, including advancing age, increased weight, and previous urinary tract infection, are important. Weight reduction and the treatment of urinary tract infections might have the additional benefit of preventing incontinence or reducing its severity.

Time Factors

Humans

Risk Factors

Sex Factors

Adult

Female

Urinary Incontinence - epidemiology

Diabetes Mellitus, Type 1 - complications

Urinary Incontinence - etiology

Details

Title: Subtitle: Risk factors for urinary incontinence among women with type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study
Creators: Aruna V Sarma - University of Michigan, Ann Arbor, Michigan 48105-7514, USA. asarma@umich.edu
Alka Kanaya
Leroy M Nyberg
John W Kusek
Eric Vittinghoff
Brandy Rutledge
Patricia A Cleary
Patricia Gatcomb
Jeanette S Brown
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group
Contributors: H Culver Boldt (Contributor) - University of Iowa, Ophthalmology and Visual Sciences
Resource Type: Journal article
Publication Details: Urology (Ridgewood, N.J.), Vol.73(6), pp.1203-1209
DOI: 10.1016/j.urology.2008.11.009
PMID: 19362350
PMCID: PMC2748226
NLM abbreviation: Urology
ISSN: 1527-9995
eISSN: 1527-9995
Publisher: United States
Grant note: PA-98-053 / PHS HHS K24 DK059294 / NIDDK NIH HHS K24 DK059294-06 / NIDDK NIH HHS
Language: English
Date published: 06/2009
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9983980015102771

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