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Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study
Journal article   Open access   Peer reviewed

Risk of Early Birth among Women with a Urinary Tract Infection: A Retrospective Cohort Study

Rebecca J Baer, Nichole Nidey, Gretchen Bandoli, Brittany D Chambers, Christina D Chambers, Sky Feuer, Deborah Karasek, Scott P Oltman, Larry Rand, Kelli K Ryckman, …
American journal of perinatology reports, Vol.11(1), pp.e5-e14
01/2021
DOI: 10.1055/s-0040-1721668
PMCID: PMC7813589
PMID: 33489437
url
https://doi.org/10.1055/s-0040-1721668View
Published (Version of record) Open Access

Abstract

Objective  The aim of the study is to evaluate the risk of preterm birth (PTB, <37 weeks) and early term (37 and 38 weeks) birth among women with an emergency department (ED) visit or hospitalization with a urinary tract infection (UTI) by trimester of pregnancy. Methods  The primary sample was selected from births in California between 2011 and 2017. UTIs were identified from the ED or hospital discharge records. Risk of PTB, by subtype, and early term birth were evaluated by trimester of pregnancy and by type of visit using log-linear regression. Risk ratios were adjusted for maternal factors. Antibiotic usage was examined in a population of privately insured women from Iowa. Results  Women with a UTI during pregnancy were at elevated risk of a birth <32 weeks, 32 to 36 weeks, and 37 to 38 weeks (adjusted risk ratios [aRRs] 1.1–1.4). Of the women with a diagnostic code for multiple bacterial species, 28.8% had a PTB. A UTI diagnosis elevated risk of PTB regardless of antibiotic treatment (aRR 1.4 for treated, aRR 1.5 for untreated). Conclusion  UTIs are associated with early birth. This association is present regardless of the trimester of pregnancy, type of PTB, and antibiotic treatment.
bacterial species Case Report early term birth preterm birth trimester of infection urinary tract infection

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