Journal article
Risk of coronary artery disease in patients with idiopathic inflammatory myopathies: A systematic review and meta-analysis of observational studies
Seminars in arthritis and rheumatism, Vol.44(1), pp.63-67
08/2014
DOI: 10.1016/j.semarthrit.2014.03.004
PMID: 24684974
Abstract
To investigate the risk of coronary artery disease in patients with idiopathic inflammatory myopathies (IIM).
We conducted a systematic review and meta-analysis of observational studies that reported odds ratios, relative risks, hazard ratios, or standardized incidence ratios comparing the risk of coronary artery disease in patients with IIM versus non-IIM participants. We searched published studies indexed in MEDLINE, EMBASE, and the Cochrane database from inception to December 2013 using the terms “coronary artery disease” OR “coronary heart disease” OR “myocardial infarction” OR “atherosclerosis” combined with the terms “dermatomyositis” OR “polymyositis” OR “Idiopathic inflammatory myopathy.” Pooled risk ratio and 95% confidence interval were calculated using a random-effect, generic inverse variance method.
Overall, four studies were identified and included for data analysis. The pooled risk ratio of CAD in patients with IIM was 2.24 (95% CI: 1.02–4.92). The statistical heterogeneity of this meta-analysis was high with an I2 of 97%.
Our study demonstrated a statistically significant increased risk of CAD among patients with IIM.
Details
- Title: Subtitle
- Risk of coronary artery disease in patients with idiopathic inflammatory myopathies: A systematic review and meta-analysis of observational studies
- Creators
- Patompong Ungprasert - Siriraj HospitalPromporn Suksaranjit - University of UtahIttikorn Spanuchart - University of Hawaiʻi at MānoaNapat Leeaphorn - Columbia UniversityNitipong Permpalung - Columbia University
- Resource Type
- Journal article
- Publication Details
- Seminars in arthritis and rheumatism, Vol.44(1), pp.63-67
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.semarthrit.2014.03.004
- PMID
- 24684974
- ISSN
- 0049-0172
- eISSN
- 1532-866X
- Language
- English
- Date published
- 08/2014
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984359773602771
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