Role of CaCO3 alone and CaCO3 plus vitamin D3 in terms of calcium phosphorus product in chronic kidney diseases

L Adhikary; S Acharya; L Acharya

doi:10.33314/jnhrc.v0i0.258

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Role of CaCO3 alone and CaCO3 plus vitamin D3 in terms of calcium phosphorus product in chronic kidney diseases

Journal article

Open access

Role of CaCO3 alone and CaCO3 plus vitamin D3 in terms of calcium phosphorus product in chronic kidney diseases

L Adhikary, S Acharya and L Acharya

Journal of Nepal Health Research Council, Vol.9(1), p.67

04/2011

DOI: 10.33314/jnhrc.v0i0.258

PMID: 22929717

Appears in Diamond Open Access

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Abstract

CaCO3 alone and CaCO3 plus vitamin D3 metabolites are commonly prescribed in CKD patients. The objective of this study is to analyze the changes in Ca x P product, calcium level and phosphorus level in CKD patients receiving calcium carbonate alone and calcium carbonate with vitamin D3 in combination. A prospective, cross sectional study among CKD patients under maintenance hemodialysis two times a week were studied over a period of one year. The patients were divided into two groups receiving oral CaCO3 alone and CaCO3 plus vitamin D3 once a day. The patients were followed for 1 month and result of Ca x P product was analyzed accordingly. Mean decrease of Ca x P product in CaCO3 group is (50.42+/-8.85 to 47 +/-6.63) in one month, p value =0.001(0.6-5) and CI- 95%. There is also significant reduction of phosphorus level in CaCO3 group than CaCO3 plus vitamin D3 group. Mean decrease in phosphorus in CaCO3 group is (5.51+/-0.76 to 5.17+/- 0.05) in one month. P value =0.01(0.14-0.53) and CI 95%. There is a significant decrease in Ca x P product and phosphorus level was observed in CKD patients taking CaCO3 alone.

Nepal

Adult

Antacids - therapeutic use

Calcium - metabolism

Calcium Carbonate - therapeutic use

Cholecalciferol - therapeutic use

Cross-Sectional Studies

Drug Therapy, Combination - methods

Female

Humans

Kidney Failure, Chronic - drug therapy

Male

Middle Aged

Phosphorus - metabolism

Prospective Studies

Renal Dialysis

Vitamins - therapeutic use

Details

Title: Subtitle: Role of CaCO3 alone and CaCO3 plus vitamin D3 in terms of calcium phosphorus product in chronic kidney diseases
Creators: L Adhikary - Department of Medicine, Kathmandu Medical College Teaching Hospital, Sinamangal, Nepal. adhikarylaxu@gmail.com
S Acharya
L Acharya - University of Iowa, Internal Medicine
Resource Type: Journal article
Publication Details: Journal of Nepal Health Research Council, Vol.9(1), p.67
DOI: 10.33314/jnhrc.v0i0.258
PMID: 22929717
eISSN: 1999-6217
Language: English
Date published: 04/2011
Academic Unit: General Internal Medicine; Internal Medicine
Record Identifier: 9984130701402771

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