Journal article
Role of Doppler US in screening for carotid atherosclerotic disease
Radiology, Vol.197(3), pp.635-643
1995
DOI: 10.1148/radiology.197.3.7480731
PMID: 7480731
Abstract
Purpose: To evaluate Doppler ultrasound (US) as a screening modality before arteriography for extracranial carotid artery disease.
Materials and methods: The net benefit in stroke reduction from screening with Doppler US was calculated on the basis of literature estimates of disease prevalence, risk reduction data, and locally validated sensitivities and specificities for detection of carotid artery stenosis and occlusion in 215 patients.
Results: Screening a symptomatic population demonstrated a net stroke reduction. Screening asymptomatic populations with a 20% prevalence of > or = 60% stenosis also yielded a net stroke reduction. Screening low-prevalence (5%) asymptomatic populations produced a small benefit, which was lost if arteriographic or surgical complications increased slightly. Arteriographic confirmation of the US diagnosis of occlusion produced a small benefit only in the symptomatic population.
Conclusion: Screening symptomatic and high-prevalence asymptomatic populations with US reduces stroke. Increased arteriographic or surgical complication rates reduce the benefit of screening in any population.
Details
- Title: Subtitle
- Role of Doppler US in screening for carotid atherosclerotic disease
- Creators
- C. P DERDEYN - Washington univ. school medicine, Mallinckrodt inst. radiology, St Louis MO, United StatesW. J POWERS - Washington univ. school medicine, Mallinckrodt inst. radiology, St Louis MO, United StatesC. J MORAN - Washington univ. school medicine, Mallinckrodt inst. radiology, St Louis MO, United StatesD. T CROSS - Washington univ. school medicine, Mallinckrodt inst. radiology, St Louis MO, United StatesB. T ALLEN - Washington univ. school medicine, Mallinckrodt inst. radiology, St Louis MO, United States
- Resource Type
- Journal article
- Publication Details
- Radiology, Vol.197(3), pp.635-643
- Publisher
- Radiological Society of North America; Oak Brook, IL
- DOI
- 10.1148/radiology.197.3.7480731
- PMID
- 7480731
- ISSN
- 0033-8419
- eISSN
- 1527-1315
- Language
- English
- Date published
- 1995
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020646002771
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