Journal article
Role of Ultrasound Elastography in Patient Selection for Prostatic Artery Embolization
Journal of vascular and interventional radiology, Vol.32(10), pp.1410-1416
10/01/2021
DOI: 10.1016/j.jvir.2021.07.018
PMID: 34333109
Abstract
Purpose: To determine the effects of prostatic artery embolization (PAE) on prostate elasticity as assessed using ultrasound elastography (US-E) and to describe baseline US-E's potential role in patient selection.
Materials and Methods: This was a prospective investigation that included 20 patients undergoing PAE to treat lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH). US-E with measurement of the prostatic elastic modulus (EM) and shear wave velocity (SWV) was performed before PAE and at 1-month follow-up. Baseline, 3-month, and 1-year follow-up evaluations included prostate-specific antigen, uroflowmetry, pelvic magnetic resonance imaging, and clinical assessment using the International Prostate Symptom Score (IPSS) and quality of life (QoL) metrics.
Results: Seventeen patients entered statistical analysis. US-E showed a significant reduction in mean prostatic EM (34.4 kPa vs 46.3 kPa, similar to 24.7%, P <.0001) and SWV (3.55 m/s vs 4.46 m/s, similar to 20.0%, P <.0001) after PAE. There were moderate positive correlations between baseline EM and 1-year IPSS (R = 0.62, P = .007) and between baseline SWVand 1-year IPSS (R = 0.68, P = .002). Baseline SWV >= 5.59 m/s and baseline EM >= 50.14 kPa were associated with suboptimal IPSS and QoL outcomes after PAE with high degrees of sensitivity (100%) and specificity (69-100%).
Conclusions: PAE led to a positive effect on the BPH dynamic component related to prostatic elasticity. There was a moderate positive correlation between baseline prostatic elastographic parameters and 12-month IPSS. Measurement of baseline elastographic characteristics may become useful for the evaluation and selection of patients for PAE.
Details
- Title: Subtitle
- Role of Ultrasound Elastography in Patient Selection for Prostatic Artery Embolization
- Creators
- Andre Moreira de Assis - Universidade de São PauloAirton Mota Moreira - Hospital Sírio-LibanêsFrancisco Cesar Carnevale - Universidade de São PauloAntonio Sergio Zafred Marcelino - Sirio Libanes Hosp, Radiol Dept, Sao Paulo, BrazilAlberto Azoubel Antunes - Universidade de São PauloMiguel Srougi - Universidade de São PauloGiovanni Guido Cerri - Hospital Sírio-Libanês
- Resource Type
- Journal article
- Publication Details
- Journal of vascular and interventional radiology, Vol.32(10), pp.1410-1416
- Publisher
- Elsevier
- DOI
- 10.1016/j.jvir.2021.07.018
- PMID
- 34333109
- ISSN
- 1051-0443
- eISSN
- 1535-7732
- Number of pages
- 7
- Language
- English
- Date published
- 10/01/2021
- Academic Unit
- Radiology
- Record Identifier
- 9984697719002771
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