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Role of lateral parabrachial nucleus in the inhibition of water intake produced by right atrial stretch
Journal article   Open access   Peer reviewed

Role of lateral parabrachial nucleus in the inhibition of water intake produced by right atrial stretch

Lynne E Ohman and Alan Kim Johnson
Brain research, Vol.695(2), pp.275-278
1995
DOI: 10.1016/0006-8993(95)00929-K
PMID: 8556345
url
https://doi.org/10.1016/0006-8993(95)00929-KView
Published (Version of record) Open Access

Abstract

Rats with either bilateral electrolytic or sham lesions of the ventrolateral portion of the lateral parabrachial nucleus (VLLPBN) were implanted with latex balloons that lay at the right superior vena cava/atrial junction (RSVC/AJ). Water intake in response to isoproterenol was measured both with and without inflation of the balloon. Water intake of the sham-lesioned rats was significantly depressed by balloon inflation during the first hour of the experiment. In contrast, water intake in the VLLPBN-lesioned rats was unaffected by balloon inflation. These results suggest that the VLLPBN is involved in the processing of afferent input from stretch-activated RSVC/AJ receptors.
Atrial volume receptor Isoproterenol Lateral parabrachial nucleus Rat Water intake

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