Journal article
Role of robot-assisted radical prostatectomy in the management of high-risk prostate cancer
Indian journal of urology, Vol.30(4), pp.410-417
10/01/2014
DOI: 10.4103/0970-1591.142067
PMCID: PMC4220381
PMID: 25378823
Abstract
We aimed to evaluate the role of robot-assisted radical prostatectomy (RARP) in the management of high-risk prostate cancer (PCa), with a focus on oncological, functional and perioperative outcomes. Further, we also aimed to briefly describe our novel modification to conventional RARP that allows immediate organ retrieval and examination for intra-operative surgical margin assessment. A literature search of PubMed was performed for articles on the management of high-risk PCa. Papers written in English and concerning clinical outcomes following RARP for locally advanced and high-risk PCa were selected. Outcomes data from our own center were also included. A total of 10 contemporary series were evaluated. Biopsy Gleason score >= 8 was the most common cause for classification of patients into the high-risk PCa group. Biochemical failure rate, in the few series that looked at long-term follow-up, varied from 9% to 26% at 1 year. The positive surgical margin rate varied from 12% to 53.3%. Urinary continence rates varied from 78% to 92% at 1 year. The overall complication rates varied from 2.4% to 30%, with anastomotic leak and lymphocele being the most common complications. Long-term data on oncological control following RARP in high-risk patients is lacking. Short-term oncological outcomes and functional outcomes are equivalent to open radical prostatectomy (RP). Safety outcomes are better in patients undergoing RARP when compared with open RP. Improved tools for predicting the presence of organ-confined disease (OCD) are available. High-risk patients with OCD would be ideal candidates for RARP and would benefit most from surgery alone.
Details
- Title: Subtitle
- Role of robot-assisted radical prostatectomy in the management of high-risk prostate cancer
- Creators
- Akshay Sood - Ford Motor CompanyWooju Jeong - Henry Ford HospitalDeepansh Dalela - Henry Ford HospitalDane E. Klett - Henry Ford HospitalFiras Abdollah - Henry Ford HospitalJesse D. Sammon - Ford Motor CompanyMani Menon - Henry Ford HospitalMahendra Bhandari - Henry Ford Hospital
- Resource Type
- Journal article
- Publication Details
- Indian journal of urology, Vol.30(4), pp.410-417
- DOI
- 10.4103/0970-1591.142067
- PMID
- 25378823
- PMCID
- PMC4220381
- NLM abbreviation
- Indian J Urol
- ISSN
- 0970-1591
- eISSN
- 1998-3824
- Publisher
- MEDKNOW PUBLICATIONS & MEDIA PVT LTD
- Number of pages
- 8
- Language
- English
- Date published
- 10/01/2014
- Academic Unit
- Urology
- Record Identifier
- 9984949193002771
Metrics
1 Record Views