Journal article
Role of superoxide dismutase in cancer: a review
Cancer research (Chicago, Ill.), Vol.39(4), pp.1141-1149
04/1979
PMID: 217531
Abstract
Diminished amounts of manganese-containing superoxide dismutase have been found in all the tumors examined to date. Lowered amounts of the copper-zinc-containing superoxide dismutase have been found in many, but not all, tumors. At the same time, tumors have been shown to produce superoxide radicals. It is shown how diminished enzyme activities along with radical production may lead to many of the observed properties of cancer cells. The apparent exploitation of the differences between normal and cancer cell superoxide dismutase activity in the treatment of cancer is discussed.
Details
- Title: Subtitle
- Role of superoxide dismutase in cancer: a review
- Creators
- L W OberleyG R Buettner
- Resource Type
- Journal article
- Publication Details
- Cancer research (Chicago, Ill.), Vol.39(4), pp.1141-1149
- Publisher
- United States
- PMID
- 217531
- ISSN
- 0008-5472
- eISSN
- 1538-7445
- Language
- English
- Date published
- 04/1979
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984047858802771
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