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Roles of TRAF molecules in B lymphocyte function
Journal article   Open access   Peer reviewed

Roles of TRAF molecules in B lymphocyte function

Ping Xie, Zachary J Kraus, Laura L Stunz and Gail A Bishop
Cytokine & growth factor reviews, Vol.19(3), pp.199-207
2008
DOI: 10.1016/j.cytogfr.2008.04.002
PMCID: PMC2495079
PMID: 18499506
url
https://www.ncbi.nlm.nih.gov/pmc/articles/2495079View
Open Access

Abstract

Tumor necrosis factor receptor associated factors (TRAFs) play a variety of interesting and important roles in the regulation of B lymphocyte function. They act both as cytoplasmic regulatory molecules, and as signal transducers for receptors involved in both innate and adaptive humoral immune responses. In this brief review, we highlight the current state of knowledge of the diverse roles of TRAF molecules in the functions of B lymphocytes.
B lymphocyte CD40 TRAF Signal transducers Humoral immune responses

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