Journal article
Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity
Organic & biomolecular chemistry, Vol.10(26), pp.5039-5044
01/01/2012
DOI: 10.1039/c2ob25192b
PMID: 22565549
Abstract
Phytochemical study of the leaves of the medicinal plant Isodon rubescens led to the isolation of three novel abietane diterpenoids, rubesanolides C-E (1-3). These diterpenes contain a unique.-lactone subgroup formed between C-8 and C-20. Their structures were determined from analysis of spectroscopic data, and were further confirmed by X-ray crystallographic data. The compounds were evaluated for their antibacterial activity, and rubesanolide D (2) demonstrated inhibition activity against biofilm formation of the dental bacterium Streptococcus mutans.
Details
- Title: Subtitle
- Rubesanolides C-E: abietane diterpenoids isolated from Isodon rubescens and evaluation of their anti-biofilm activity
- Creators
- Juan Zou - Guiyang College of Traditional Chinese MedicineLutai Pan - Guiyang College of Traditional Chinese MedicineQiji Li - Guiyang College of Traditional Chinese MedicineJianxin Pu - Kunming Institute of BotanyPing Yao - University of Illinois at ChicagoMin Zhu - University of IowaJeffrey A. Banas - University of IowaHongjie Zhang - Hong Kong Baptist UniversityHandong Sun - Kunming Institute of Botany
- Resource Type
- Journal article
- Publication Details
- Organic & biomolecular chemistry, Vol.10(26), pp.5039-5044
- Publisher
- Royal Soc Chemistry
- DOI
- 10.1039/c2ob25192b
- PMID
- 22565549
- ISSN
- 1477-0520
- eISSN
- 1477-0539
- Number of pages
- 6
- Grant note
- (2008) 36 / Science and Technology Department of Guiyang
- Language
- English
- Date published
- 01/01/2012
- Academic Unit
- Pediatric Dentistry; Dental Research
- Record Identifier
- 9984367623002771
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