Rural Residence and Antihypertensive Medication Use in US Stroke Survivors

Phoebe M Tran; Lam T Tran; Cenjing Zhu; Tiffany Chang; Inna P Powers; Larry B Goldstein; Judith H Lichtman

doi:10.1161/JAHA.122.026678

Back

Rural Residence and Antihypertensive Medication Use in US Stroke Survivors

Journal article

Open access

Peer reviewed

Rural Residence and Antihypertensive Medication Use in US Stroke Survivors

Phoebe M Tran, Lam T Tran, Cenjing Zhu, Tiffany Chang, Inna P Powers, Larry B Goldstein and Judith H Lichtman

Journal of the American Heart Association, Vol.11(15), pp.e026678-e026678

08/02/2022

DOI: 10.1161/JAHA.122.026678

PMCID: PMC9375512

PMID: 35862140

Files and links (1)

url

https://doi.org/10.1161/JAHA.122.026678View

Published (Version of record) Open Access

Abstract

Background Relatively greater increases in hypertension prevalence among US rural residents may contribute to geographic disparities in recurrent stroke. There is limited US information on poststroke antihypertensive medication use by rural/urban residence. We assessed antihypertensive use and lifestyle characteristics for US rural compared with urban stroke survivors and residence-based trends in use between 2005 and 2019. Methods and Results US stroke survivors with hypertension were identified in the 2005 to 2019 national Behavioral Risk Factor Surveillance System surveys. We ascertained the survey-weighted prevalence of reported antihypertensive use and lifestyle characteristics (ie, physical activity, diabetes, cholesterol, body mass index, and smoking) among respondents with hypertension in odd years over this period by rural/urban residence. Separate trend analyses were used to detect changes in use over time. Survey-weighted logistic regression was used to calculate unadjusted and adjusted (sociodemographic and lifestyle factors) odds ratios for antihypertensive use by year. Our study included 82 175 individuals (36.4% rural residents). Lifestyle characteristics were similar between rural and urban residents except for higher smoking prevalence among rural residents. Antihypertensive use was similar between rural and urban stroke survivors in unadjusted and adjusted analyses (>90% in both populations). Trend analyses showed a small but significant increase in antihypertensive use over time among urban ( =0.033) but not rural stroke survivors ( =0.587). Conclusions Our findings indicate that poststroke antihypertensive use is comparable in rural and urban residents with a reported history of hypertension, but additional work is merited to identify reasons for a trend for increased use of these drugs among urban residents.

Antihypertensive Agents - therapeutic use

Humans

Hypertension - drug therapy

Hypertension - epidemiology

Prevalence

Risk Factors

Rural Population

Stroke - drug therapy

Stroke - epidemiology

Survivors

Urban Population

Details

Title: Subtitle: Rural Residence and Antihypertensive Medication Use in US Stroke Survivors
Creators: Phoebe M Tran - University of Tennessee at Knoxville
Lam T Tran - University of Michigan–Ann Arbor
Cenjing Zhu - Yale University
Tiffany Chang - Yale University
Inna P Powers - University of Colorado Denver
Larry B Goldstein - University of Kentucky
Judith H Lichtman - Yale University
Resource Type: Journal article
Publication Details: Journal of the American Heart Association, Vol.11(15), pp.e026678-e026678
DOI: 10.1161/JAHA.122.026678
PMID: 35862140
PMCID: PMC9375512
ISSN: 2047-9980
eISSN: 2047-9980
Grant note: R01 AG056628 / NIA NIH HHS UL1 TR001863 / NCATS NIH HHS T32 HG000040 / NHGRI NIH HHS
Language: English
Date published: 08/02/2022
Academic Unit: Stead Family Department of Pediatrics; Rheumatology, Allergy, and Immunology
Record Identifier: 9984702818102771

Metrics

3 Record Views

1 Times Cited - Web of Science

See more details