Journal article
Safe and Appropriate Use of Methadone in Hospice and Palliative Care: Expert Consensus White Paper
Journal of pain and symptom management, Vol.57(3), pp.635-645.e4
03/2019
DOI: 10.1016/j.jpainsymman.2018.12.001
PMID: 30578934
Abstract
Methadone has several unique characteristics that make it an attractive option for pain relief in serious illness, but the safety of methadone has been called into question after reports of a disproportionate increase in opioid-induced deaths in recent years. The American Pain Society, College on Problems of Drug Dependence, and the Heart Rhythm Society collaborated to issue guidelines on best practices to maximize methadone safety and efficacy, but guidelines for the end-of-life scenario have not yet been developed. A panel of 15 interprofessional hospice and palliative care experts from the U.S. and Canada convened in February 2015 to evaluate the American Pain Society methadone recommendations for applicability in the hospice and palliative care setting. The goal was to develop guidelines for safe and effective management of methadone therapy in hospice and palliative care. This article represents the consensus opinion of the hospice and palliative care experts for methadone use at end of life, including guidance on appropriate candidates for methadone, detail in dosing, titration, and monitoring of patients' response to methadone therapy.
Details
- Title: Subtitle
- Safe and Appropriate Use of Methadone in Hospice and Palliative Care: Expert Consensus White Paper
- Creators
- Mary Lynn McPherson - University of Maryland School of Pharmacy, Baltimore, Maryland, USAKathryn A Walker - University of Maryland School of Pharmacy, Baltimore, Maryland, USAMellar P Davis - Geisinger Medical Center, Danville, Philadelphia, USAEduardo Bruera - Palliative, Rehabilitation & Integrative Medicine Department, University of Texas MD Anderson Cancer Center, Houston, Texas, USAAkhila Reddy - The University of Texas MD Anderson Cancer Center, Houston, Texas, USAJudith Paice - Division of Hematology-Oncology, Northwestern University, Chicago, Illinois, USAKasey Malotte - Advanced Practice Pharmacist Supportive Care Medicine Cedars-Sinai Medical Center, Los Angeles, California, USADawn Kashelle Lockman - Hospice & Palliative Care, University of Iowa College of Pharmacy, Iowa City, Iowa, USACharles Wellman - Hospice of the Western Reserve, Cleveland, Ohio, USAShelley Salpeter - Stanford University School of Medicine, Stanford, California, USANina M Bemben - Wolters Kluwer, Chicago, Illinois, USAJames B Ray - University of Iowa College of Pharmacy, Iowa City, Iowa, USABernard J Lapointe - Eric M. Flanders Chair in Palliative Medicine, McGill University, Montreal, CanadaRoger Chou - Division of General Internal Medicine and Geriatrics, OHSU, USA
- Resource Type
- Journal article
- Publication Details
- Journal of pain and symptom management, Vol.57(3), pp.635-645.e4
- DOI
- 10.1016/j.jpainsymman.2018.12.001
- PMID
- 30578934
- NLM abbreviation
- J Pain Symptom Manage
- ISSN
- 0885-3924
- eISSN
- 1873-6513
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 03/2019
- Academic Unit
- Pharmacy Practice and Science; Office of Consultation and Research in Medical Education; Internal Medicine
- Record Identifier
- 9984065694602771
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