Journal article
Safety and efficacy using a detachable tip microcatheter in the embolization of pediatric arteriovenous malformations
Child's nervous system, Vol.30(6), pp.1099-1107
06/2014
DOI: 10.1007/s00381-014-2404-9
PMID: 24671157
Abstract
The treatment of deep-seeded pediatric brain arteriovenous malformations (AVMs) remains a challenging task. We describe our experience using a new detachable tip microcatheter in the embolization of brain arteriovenous malformations, pial arteriovenous fistulas, and vein of Galen malformations. We describe the safety and efficacy using a new detachable tip microcatheter in the treatment of pediatric deep brain arteriovenous malformations, pial malformations, and vein of Galen malformations.During a period of 9 months from March 2013 through January 2014, 11 pediatric patients in 14 procedures with 27 total injections were selected for treatment with a detachable tip under Food and Drug Administration (FDA) compassionate use exemption and were admitted to our department for treatment of their brain AVM using a liquid embolic agent and a detachable tip microcatheter. The ages of the patients ranged from 3 months to 18 years old.Of the 27 total injections done, the tip detached in seven cases. For the 16 n-BCA injections, the tip detached six times (37.5 %), and for the 11 Onyx injections, the tip detached one time (9 %). There were no cases of premature microcatheter detachment during normal vessel navigation.The introduction of these detachable tip microcatheters allows for a safe and relaxed injection that permits a true circumferential occlusion, and may further permit filling a larger amount of angioarchitecture without the risk of distal migration, or vessel damage during the usual rapid removal of non detachable micocatheters.
Details
- Title: Subtitle
- Safety and efficacy using a detachable tip microcatheter in the embolization of pediatric arteriovenous malformations
- Creators
- David Altschul - Center for Endovascular Surgery, Hyman-Newman Institute for Neurology and Neurosurgery, Suite 10G Mount Sinai-Roosevelt Hospital 1000 Tenth Ave. New York NY 10019 USASrinivasan Paramasivam - Center for Endovascular Surgery, Hyman-Newman Institute for Neurology and Neurosurgery, Suite 10G Mount Sinai-Roosevelt Hospital 1000 Tenth Ave. New York NY 10019 USASantiago Ortega-Gutierrez - Center for Endovascular Surgery, Hyman-Newman Institute for Neurology and Neurosurgery, Suite 10G Mount Sinai-Roosevelt Hospital 1000 Tenth Ave. New York NY 10019 USAJohanna Fifi - Center for Endovascular Surgery, Hyman-Newman Institute for Neurology and Neurosurgery, Suite 10G Mount Sinai-Roosevelt Hospital 1000 Tenth Ave. New York NY 10019 USAAlejandro Berenstein - Center for Endovascular Surgery, Hyman-Newman Institute for Neurology and Neurosurgery, Suite 10G Mount Sinai-Roosevelt Hospital 1000 Tenth Ave. New York NY 10019 USA
- Resource Type
- Journal article
- Publication Details
- Child's nervous system, Vol.30(6), pp.1099-1107
- DOI
- 10.1007/s00381-014-2404-9
- PMID
- 24671157
- NLM abbreviation
- Childs Nerv Syst
- ISSN
- 0256-7040
- eISSN
- 1433-0350
- Publisher
- Springer Berlin Heidelberg; Berlin/Heidelberg
- Language
- English
- Date published
- 06/2014
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020621702771
Metrics
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