Journal article
Salvage laryngectomy and laryngopharyngectomy: Multicenter review of outcomes associated with a reconstructive approach
Head & neck, Vol.41(1), pp.16-29
01/2019
DOI: 10.1002/hed.25192
PMID: 30508265
Abstract
Background: Surgeons have developed various reconstructive techniques to minimize the rate of pharyngocutaneous fistula and optimize functional outcome after salvage laryngectomy or laryngopharyngectomy. Methods: Multicenter retrospective review at 33 institutions of 486 patients with a history of squamous cell carcinoma (SCC) of the larynx or hypopharynx previously treated with primary chemoradiotherapy (CRT) who required salvage surgery. Outcomes evaluated were overall fistula rate, fistula requiring reoperation, and 12‐month speech and swallowing function. Results: Primary closure of the hypopharynx was associated with a statistically higher overall fistula rate and fistula requiring reoperation compared to reconstruction with vascularized tissue augmentation. Vascularized tissue augmentation with muscle led to worse 12‐month “understandability of speech” and “nutritional mode” scores compared to vascularized tissue augmentation without muscle. Conclusion: Vascularized tissue augmentation reduces the overall fistula rate and fistula requiring reoperation but vascularized tissue augmentation with muscle may impair speech and swallowing outcomes.
Details
- Title: Subtitle
- Salvage laryngectomy and laryngopharyngectomy: Multicenter review of outcomes associated with a reconstructive approach
- Creators
- Lance E OxfordRodrigo BayonHan ZhangNitin A PagedarKristi E ChangMark UrkenHenry T HoffmanCathy LazarusJenna CheneyJoseph ScharpfMatthew MillerMichael A FritzLiana PuscasMarc CohenJoshua D HornigAlex M MlynarekBrett MilesEric GendenEyal SelaUrjeet A PatelMichael P HierMarita TengMatthew M HanasonoAlice C LinBadr IbrahimPeirong YuJames P MaloneEben L RosenthalLisa ClemonsDaniel A O'ConnellKhalid AnsariJeffrey R HarrisHadi SeikalyMauricio A MorenoQuang LuuJoel JacobsonD. Gregory FarwellKeith BlackwellSoroush ZaghiVishad NabiliSteven J WangBridget C BurgessKeith CasperJulie GoddardYelizaveta ShnayderJustin BondKevin J SykesDouglas A GirodTerance T TsueThomas J GalThomas Justin WayJason M LeibowitzAvinash V MantravadiAriel B GrobmanDonald T WeedFrancisco CivantosDouglas B ChepehaAndrew RoskoEmily BelileEric J. P ChanowskiGregory T WolfCarol R BradfordMark E PrinceJeff S MoyerMatthew E SpectorSamir S KhariwalaAmy Anne LassigJeffrey B JorgensenJason ShowmakerLauren A UmstattdElizabeth LaiRobert P ZitschGregory J RennerOleg MilitsakhJamie FlohrPaul van der SlootLarry L MyersBaran D SumerJohn M TruelsonDavid GoldsteinRalph GilbertJonathan IrishPatrick GullaneDale BrownLuke BuchmannJason HuntMark J JamesonDavid C ShonkaNeal D FutranEduardo MendezKevin FungMathieu BelzileSamuel A DowthwaiteJohn H YooAnthony C NicholsJason H FranklinBrian NussenbaumShaun DesaiMicrovascular Committee of the American Academy of Otolaryngology-Head & Neck SurgeryJason Diaz
- Resource Type
- Journal article
- Publication Details
- Head & neck, Vol.41(1), pp.16-29
- DOI
- 10.1002/hed.25192
- PMID
- 30508265
- NLM abbreviation
- Head Neck
- ISSN
- 1043-3074
- eISSN
- 1097-0347
- Number of pages
- 14
- Language
- English
- Date published
- 01/2019
- Academic Unit
- Radiation Oncology; Otolaryngology
- Record Identifier
- 9984007177302771
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