Sarcopenia is a Predictor of Surgical Morbidity in Inflammatory Bowel Disease

Mark Pedersen; John Cromwell; Peter Nau

doi:10.1097/MIB.0000000000001166

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Sarcopenia is a Predictor of Surgical Morbidity in Inflammatory Bowel Disease

Journal article

Open access

Peer reviewed

Sarcopenia is a Predictor of Surgical Morbidity in Inflammatory Bowel Disease

Mark Pedersen, John Cromwell and Peter Nau

Inflammatory bowel diseases, Vol.23(10), pp.1867-1872

10/2017

DOI: 10.1097/MIB.0000000000001166

PMID: 28604415

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https://doi.org/10.1097/MIB.0000000000001166View

Published (Version of record) Open Access

Abstract

Sarcopenia is associated with an increased risk of operative morbidity and mortality. The impact of sarcopenia in inflammatory bowel disease (IBD) has not been evaluated. This study assessed the role of sarcopenia on operative outcomes in IBD. A retrospective review of American College of Surgeons National Surgical Quality Improvement Program data of patients with IBD was completed. Records were abstracted for comorbidities and perioperative complications. The Hounsfield unit average calculation was used from preoperative computed tomography (CT). Criteria for sarcopenia were based on the lowest 25th percentile. Complications were graded using the Clavien-Dindo classification system. Statistical analysis was completed using SAS. There were 178 patients included. Sarcopenic patients were more likely to be older (P = 0.001), have hypertension (odds ratio = 2.23), and be diabetic (5.27). In those patients younger than 40 years, sarcopenia was an independent predictor of complications. This subset was significantly more likely to have a normal or elevated body mass index. In this population, the average age of sarcopenic patients is increased from those who do not meet criteria. Among patients younger than 40 years, sarcopenia affects surgical outcomes. Assessment of sarcopenia can be used to improve preoperative management and describe risks before surgery in patients with IBD.

Humans

Middle Aged

Sarcopenia - complications

Male

Tomography, X-Ray Computed

Young Adult

Reoperation - statistics & numerical data

Aged, 80 and over

Adult

Female

Retrospective Studies

Inflammatory Bowel Diseases - complications

Length of Stay - statistics & numerical data

Risk Assessment

Comorbidity

Risk Factors

Sarcopenia - diagnostic imaging

Logistic Models

Treatment Outcome

Postoperative Complications - epidemiology

Sepsis - mortality

Iowa

Muscle, Skeletal - diagnostic imaging

Adolescent

Inflammatory Bowel Diseases - surgery

ROC Curve

Aged

Details

Title: Subtitle: Sarcopenia is a Predictor of Surgical Morbidity in Inflammatory Bowel Disease
Creators: Mark Pedersen - The University of Iowa Hospitals and Clinics, Iowa City, Iowa
John Cromwell
Peter Nau
Resource Type: Journal article
Publication Details: Inflammatory bowel diseases, Vol.23(10), pp.1867-1872
Publisher: United States
DOI: 10.1097/MIB.0000000000001166
PMID: 28604415
ISSN: 1078-0998
eISSN: 1536-4844
Language: English
Date published: 10/2017
Academic Unit: Surgery; Anesthesia
Record Identifier: 9984051785102771

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