Journal article
Sarcopenia is a risk factor for complications and an independent predictor of hospital length of stay in trauma patients
The Journal of surgical research, Vol.221, pp.161-166
01/2018
DOI: 10.1016/j.jss.2017.08.018
PMID: 29229123
Abstract
Sarcopenia is an independent risk factor for adverse outcomes in critically ill patients. The impact of sarcopenia on morbidity and length of stay in a trauma population has not been completely defined. This project evaluated the influence of sarcopenia on patients admitted to the trauma service.
A retrospective review of 778 patients presenting as a trauma alert at a single institution from 2012-2014 was completed. Records were abstracted for comorbidities and hospital complications. The Hounsfield Unit Area Calculation was collected from admission computed tomography scans. Criteria for sarcopenia were based on the lowest 25th percentile of muscle density measurements. Relationships to patient outcomes were evaluated by univariate and multivariable regression or analyses of variance, when applicable.
A total of 432 (55.6%) patients suffered a complication. Sarcopenia was associated with overall complications (P < 0.0001, relative risk 2.54, confidence interval 1.78-3.61) and was an independent risk factor for catheter-associated urinary tract infections (P = 0.011), wound infections (P = 0.011), need for reintubation (P = 0.0062), and length of hospitalization (P = 0.0007). Incorporating sarcopenia into a novel length of stay calculator showed increased prognostic ability for prolonged length of stay over Abbreviated Injury Scale alone (P = 0.0002).
Sarcopenia is an independent risk factor for adverse outcomes and increased length of stay in trauma patients. Prognostic algorithms incorporating sarcopenia better predict hospital length of stay. Identification of patients at risk may allow for targeted interventions early in the patient's hospital course.
Details
- Title: Subtitle
- Sarcopenia is a risk factor for complications and an independent predictor of hospital length of stay in trauma patients
- Creators
- James DeAndrade - The University of Iowa Hospitals and Clinics, Iowa City, IowaMark Pedersen - The University of Iowa Hospitals and Clinics, Iowa City, IowaLuis Garcia - The University of Iowa Hospitals and Clinics, Iowa City, IowaPeter Nau - The University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address: peter-nau@uiowa.edu
- Resource Type
- Journal article
- Publication Details
- The Journal of surgical research, Vol.221, pp.161-166
- Publisher
- United States
- DOI
- 10.1016/j.jss.2017.08.018
- PMID
- 29229123
- ISSN
- 0022-4804
- eISSN
- 1095-8673
- Language
- English
- Date published
- 01/2018
- Academic Unit
- Surgery; Anesthesia
- Record Identifier
- 9984051762602771
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