Journal article
Sclerosing mesenteritis in small bowel transplantation: possible manifestation of acute vascular rejection
Transplantation proceedings, Vol.35(8), pp.3057-3060
2003
DOI: 10.1016/j.transproceed.2003.10.016
PMID: 14697979
Abstract
Acute rejection of human small bowel allografts is characterized by clinical symptoms combined with characteristic morphologic alterations. The typical geographic distribution of acute rejection in the bowel is involvement of the intestinal parenchyma, which can be transmural, particularly when the rejection is more severe. However, little is known concerning the potential for donor-derived soft tissue adjacent to the bowel to become involved by the host alloimmune response.
We describe a male patient who, several weeks after combined small bowel and liver transplantation, demonstrated sclerosing mesenteritis with vasculitis and acute rejection of the bowel.
The vascular lesions in the mesentery demonstrated increased IgG deposition and the patient developed an alloantibody to the donor.
The changes described herein may represent a novel presentation of acute vascular rejection.
Details
- Title: Subtitle
- Sclerosing mesenteritis in small bowel transplantation: possible manifestation of acute vascular rejection
- Creators
- P Ruiz - University of MiamiM Suarez - University of MiamiS Nishida - University of MiamiV de la Cruz - University of MiamiM Nicolas - University of MiamiD Weppler - University of MiamiA Khaled - University of MiamiP Bejarano - University of MiamiT Kato - University of MiamiN Mittal - University of MiamiM Icardi - University of IowaA Tzakis - University of Miami
- Resource Type
- Journal article
- Publication Details
- Transplantation proceedings, Vol.35(8), pp.3057-3060
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.transproceed.2003.10.016
- PMID
- 14697979
- ISSN
- 0041-1345
- eISSN
- 1873-2623
- Language
- English
- Date published
- 2003
- Academic Unit
- Pathology
- Record Identifier
- 9984201246602771
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