Journal article
Screening for Celiac Disease: US Preventive Services Task Force Recommendation Statement
JAMA : the journal of the American Medical Association, Vol.317(12), pp.1252-1257
03/28/2017
DOI: 10.1001/jama.2017.1462
PMID: 28350936
Abstract
Celiac disease is caused by an immune response in persons who are genetically susceptible to dietary gluten, a protein complex found in wheat, rye, and barley. Ingestion of gluten by persons with celiac disease causes immune-mediated inflammatory damage to the small intestine.
To issue a new US Preventive Services Task Force (USPSTF) recommendation on screening for celiac disease.
The USPSTF reviewed the evidence on the accuracy of screening in asymptomatic adults, adolescents, and children; the potential benefits and harms of screening vs not screening and targeted vs universal screening; and the benefits and harms of treatment of screen-detected celiac disease. The USPSTF also reviewed contextual information on the prevalence of celiac disease among patients without obvious symptoms and the natural history of subclinical celiac disease.
The USPSTF found inadequate evidence on the accuracy of screening for celiac disease, the potential benefits and harms of screening vs not screening or targeted vs universal screening, and the potential benefits and harms of treatment of screen-detected celiac disease.
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for celiac disease in asymptomatic persons. (I statement).
Details
- Title: Subtitle
- Screening for Celiac Disease: US Preventive Services Task Force Recommendation Statement
- Creators
- Kirsten Bibbins-Domingo - University of California, San FranciscoDavid C Grossman - Kaiser Permanente Washington Health Research InstituteSusan J Curry - University of IowaMichael J Barry - Harvard UniversityKarina W Davidson - Columbia UniversityChyke A Doubeni - University of PennsylvaniaMark Ebell - University of GeorgiaJohn W Epling Jr - Virginia TechJessica Herzstein - Independent SectorAlex R Kemper - Duke UniversityAlex H Krist - Virginia Commonwealth UniversityAnn E Kurth - Yale UniversityC Seth Landefeld - University of Alabama at BirminghamCarol M Mangione - University of California, Los AngelesMaureen G Phipps - Brown UniversityMichael Silverstein - Boston UniversityMelissa A Simon - Northwestern UniversityChien-Wen Tseng - University of Hawaiʻi at MānoaUS Preventive Services Task Force
- Resource Type
- Journal article
- Publication Details
- JAMA : the journal of the American Medical Association, Vol.317(12), pp.1252-1257
- DOI
- 10.1001/jama.2017.1462
- PMID
- 28350936
- NLM abbreviation
- JAMA
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- Language
- English
- Date published
- 03/28/2017
- Academic Unit
- Health Management and Policy; Community and Behavioral Health
- Record Identifier
- 9984367131002771
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