Journal article
Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
JAMA : the journal of the American Medical Association, Vol.316(6), pp.625-633
08/09/2016
DOI: 10.1001/jama.2016.9852
PMID: 27532917
Abstract
Elevations in levels of total, low-density lipoprotein, and non-high-density lipoprotein cholesterol; lower levels of high-density lipoprotein cholesterol; and, to a lesser extent, elevated triglyceride levels are associated with risk of cardiovascular disease in adults.
To update the 2007 US Preventive Services Task Force (USPSTF) recommendation on screening for lipid disorders in children, adolescents, and young adults.
The USPSTF reviewed the evidence on screening for lipid disorders in children and adolescents 20 years or younger--1 review focused on screening for heterozygous familial hypercholesterolemia, and 1 review focused on screening for multifactorial dyslipidemia.
Evidence on the quantitative difference in diagnostic yield between universal and selective screening approaches, the effectiveness and harms of long-term treatment and the harms of screening, and the association between changes in intermediate outcomes and improvements in adult cardiovascular health outcomes are limited. Therefore, the USPSTF concludes that the balance of benefits and harms cannot be determined.
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for lipid disorders in children and adolescents 20 years or younger. (I statement).
Details
- Title: Subtitle
- Screening for Lipid Disorders in Children and Adolescents: US Preventive Services Task Force Recommendation Statement
- Creators
- Kirsten Bibbins-Domingo - University of California, San FranciscoDavid C Grossman - Group Health CooperativeSusan J Curry - University of IowaKarina W Davidson - Columbia UniversityJohn W Epling Jr - SUNY Upstate Medical UniversityFrancisco A R García - Pima County Department of Health, Tucson, ArizonaMatthew W Gillman - Harvard UniversityAlex R Kemper - Duke UniversityAlex H Krist - Virginia Commonwealth UniversityAnn E Kurth - Yale UniversityC Seth Landefeld - University of AlabamaMichael LeFevre - University of MissouriCarol M Mangione - University of California, Los AngelesDouglas K Owens - Veterans Affairs Palo Alto Health Care System, Palo Alto, California16Stanford University, Stanford, CaliforniaWilliam R Phillips - University of WashingtonMaureen G Phipps - Brown UniversityMichael P Pignone - The University of Texas at AustinAlbert L Siu - Icahn School of Medicine at Mount SinaiUS Preventive Services Task Force
- Resource Type
- Journal article
- Publication Details
- JAMA : the journal of the American Medical Association, Vol.316(6), pp.625-633
- DOI
- 10.1001/jama.2016.9852
- PMID
- 27532917
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- Language
- English
- Date published
- 08/09/2016
- Academic Unit
- Health Management and Policy; Community and Behavioral Health
- Record Identifier
- 9984367157202771
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