Journal article
Screening for Pancreatic Cancer: US Preventive Services Task Force Reaffirmation Recommendation Statement
JAMA : the journal of the American Medical Association, Vol.322(5), pp.438-444
08/06/2019
DOI: 10.1001/jama.2019.10232
PMID: 31386141
Abstract
Pancreatic cancer is an uncommon cancer with an age-adjusted annual incidence of 12.9 cases per 100 000 person-years. However, the death rate is 11.0 deaths per 100 000 person-years because the prognosis of pancreatic cancer is poor. Although its incidence is low, pancreatic cancer is the third most common cause of cancer death in the United States. Because of the increasing incidence of pancreatic cancer, along with improvements in early detection and treatment of other types of cancer, it is estimated that pancreatic cancer may soon become the second-leading cause of cancer death in the United States.
To update the 2004 US Preventive Services Task Force (USPSTF) recommendation on screening for pancreatic cancer.
The USPSTF reviewed the evidence on the benefits and harms of screening for pancreatic cancer, the diagnostic accuracy of screening tests for pancreatic cancer, and the benefits and harms of treatment of screen-detected or asymptomatic pancreatic cancer.
The USPSTF found no evidence that screening for pancreatic cancer or treatment of screen-detected pancreatic cancer improves disease-specific morbidity or mortality, or all-cause mortality. The USPSTF found adequate evidence that the magnitude of the benefits of screening for pancreatic cancer in asymptomatic adults can be bounded as no greater than small. The USPSTF found adequate evidence that the magnitude of the harms of screening for pancreatic cancer and treatment of screen-detected pancreatic cancer can be bounded as at least moderate. The USPSTF reaffirms its previous conclusion that the potential benefits of screening for pancreatic cancer in asymptomatic adults do not outweigh the potential harms.
The USPSTF recommends against screening for pancreatic cancer in asymptomatic adults. (D recommendation).
Details
- Title: Subtitle
- Screening for Pancreatic Cancer: US Preventive Services Task Force Reaffirmation Recommendation Statement
- Creators
- Douglas K Owens - Stanford UniversityKarina W Davidson - Northwell HealthAlex H Krist - Virginia Commonwealth UniversityMichael J Barry - Harvard UniversityMichael Cabana - University of California, San FranciscoAaron B Caughey - Oregon Health & Science UniversitySusan J Curry - University of IowaChyke A Doubeni - Mayo ClinicJohn W Epling Jr - Virginia TechMartha Kubik - Temple UniversityC Seth Landefeld - University of Alabama at BirminghamCarol M Mangione - University of California, Los AngelesLori Pbert - University of Massachusetts BostonMichael Silverstein - Boston UniversityMelissa A Simon - Northwestern UniversityChien-Wen Tseng - Pacific Health Research and Education Institute, Honolulu, HawaiiJohn B Wong - Tufts UniversityUS Preventive Services Task Force
- Resource Type
- Journal article
- Publication Details
- JAMA : the journal of the American Medical Association, Vol.322(5), pp.438-444
- DOI
- 10.1001/jama.2019.10232
- PMID
- 31386141
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- Language
- English
- Date published
- 08/06/2019
- Academic Unit
- Health Management and Policy; Community and Behavioral Health
- Record Identifier
- 9984366281102771
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