Journal article
Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement
JAMA : the journal of the American Medical Association, Vol.315(21), pp.2321-2327
06/07/2016
DOI: 10.1001/jama.2016.5824
PMID: 27272583
Abstract
In 2014, 19,999 cases of syphilis were reported in the United States. Left untreated, syphilis can progress to late-stage disease in about 15% of persons who are infected. Late-stage syphilis can lead to development of inflammatory lesions throughout the body, which can lead to cardiovascular or organ dysfunction. Syphilis infection also increases the risk for acquiring or transmitting HIV infection.
To update the 2004 US Preventive Services Task Force (USPSTF) recommendation on screening for syphilis infection in nonpregnant adults. Screening for syphilis in pregnant women was updated in a separate recommendation statement in 2009 (A recommendation).
The USPSTF reviewed the evidence on screening for syphilis infection in asymptomatic, nonpregnant adults and adolescents, including patients coinfected with other sexually transmitted infections (such as HIV).
The USPSTF found convincing evidence that screening for syphilis infection in asymptomatic, nonpregnant persons at increased risk for infection provides substantial benefit. Accurate screening tests are available to identify syphilis infection in populations at increased risk. Effective treatment with antibiotics can prevent progression to late-stage disease, with small associated harms, providing an overall substantial health benefit.
The USPSTF recommends screening for syphilis infection in persons who are at increased risk for infection. (A recommendation).
Details
- Title: Subtitle
- Screening for Syphilis Infection in Nonpregnant Adults and Adolescents: US Preventive Services Task Force Recommendation Statement
- Creators
- Kirsten Bibbins-Domingo - University of California, San FranciscoDavid C Grossman - Group Health Research Institute, Seattle, WashingtonSusan J Curry - University of IowaKarina W Davidson - Columbia UniversityJohn W Epling Jr - SUNY Upstate Medical UniversityFrancisco A R García - Pima County Department of Health, Tucson, ArizonaMatthew W Gillman - Harvard Pilgrim Health CareDiane M Harper - University of LouisvilleAlex R Kemper - Duke UniversityAlex H Krist - University of RichmondAnn E Kurth - University of New HavenC Seth Landefeld - University of Alabama at BirminghamCarol M Mangione - University of California, Los AngelesWilliam R Phillips - University of WashingtonMaureen G Phipps - Brown UniversityMichael P Pignone - University of North Carolina, Chapel HillUS Preventive Services Task Force (USPSTF)
- Resource Type
- Journal article
- Publication Details
- JAMA : the journal of the American Medical Association, Vol.315(21), pp.2321-2327
- DOI
- 10.1001/jama.2016.5824
- PMID
- 27272583
- ISSN
- 0098-7484
- eISSN
- 1538-3598
- Language
- English
- Date published
- 06/07/2016
- Academic Unit
- Health Management and Policy; Community and Behavioral Health
- Record Identifier
- 9984366269402771
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