Journal article
Scurrying to Understand Sudden Expected Death in Epilepsy: Insights From Animal Models
Epilepsy currents, Vol.19(6), pp.390-396
11/2019
DOI: 10.1177/1535759719874787
PMCID: PMC6891182
PMID: 31526023
Abstract
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in patients with refractory epilepsy, accounting for up to 17% of deaths in patients with epilepsy. The pathophysiology of SUDEP has remained unclear, largely because it is unpredictable and commonly unwitnessed. This poses a great challenge to studies in patients. Recently, there has been an increase in animal studies to try to better understand the pathophysiology of SUDEP. In this current review, we focus on developments through seizure-induced death models and the preventative strategies they may reveal.
Details
- Title: Subtitle
- Scurrying to Understand Sudden Expected Death in Epilepsy: Insights From Animal Models
- Creators
- Rui Li - Department of Neurology, Carver College of Medicine, University of Iowa, IA, USA, Iowa Neuroscience Institute, Carver College of Medicine, University of Iowa, IA, USAGordon F Buchanan - Department of Neurology, Carver College of Medicine, University of Iowa, IA, USA, Iowa Neuroscience Institute, Carver College of Medicine, University of Iowa, IA, USA
- Resource Type
- Journal article
- Publication Details
- Epilepsy currents, Vol.19(6), pp.390-396
- DOI
- 10.1177/1535759719874787
- PMID
- 31526023
- PMCID
- PMC6891182
- NLM abbreviation
- Epilepsy Curr
- ISSN
- 1535-7597
- eISSN
- 1535-7511
- Grant note
- DOI: 10.13039/100000065, name: National Institute of Neurological Disorders and Stroke, award: R01 NS095842
- Language
- English
- Date published
- 11/2019
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984070142202771
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