Journal article
Seasonal Hemolysis Due to Cold-Agglutinin Syndrome
The New England Journal of Medicine, Vol.334(7), pp.437-437
02/15/1996
DOI: 10.1056/NEJM199602153340705
PMID: 8552146
Abstract
Figure 1. A 61-year-old roads inspector from Illinois presented in 1992 with hemolytic anemia and acrocyanosis and was found to have cold-agglutinin syndrome. He was treated with plasmapheresis, prednisone, and chlorambucil and then followed without therapy for two years. He continued to work, which involved spending the majority of time outdoors. The patient's cold-agglutinin titer exceeded 1:524,288, with a thermal maximum (the temperature at which agglutination occurs in vitro) of 37°C. The severity of the hemolysis, reflected by the lactate dehydrogenase concentration, was related to the ambient temperature, as illustrated. He is currently well and asymptomatic.
Details
- Title: Subtitle
- Seasonal Hemolysis Due to Cold-Agglutinin Syndrome
- Creators
- Laurie J LyckholmMichael B Edmond
- Resource Type
- Journal article
- Publication Details
- The New England Journal of Medicine, Vol.334(7), pp.437-437
- Publisher
- Massachusetts Medical Society
- DOI
- 10.1056/NEJM199602153340705
- PMID
- 8552146
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- Language
- English
- Date published
- 02/15/1996
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9983905648202771
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