Journal article
Secondary oxalosis induced acute kidney injury in allograft kidneys
Clinical kidney journal, Vol.6(1), pp.84-86
01/04/2013
DOI: 10.1093/ckj/sfs167
PMCID: PMC5094400
PMID: 27818757
Abstract
Secondary oxalosis causing acute kidney injury (AKI) has been widely reported in native kidneys but its occurrence in allograft kidneys is relatively uncommon. We present three patients with acute kidney allograft dysfunction secondary to tubular oxalate microcrystal deposits confirmed on allograft biopsy in the setting of acute gastrointestinal dysfunction. These three patients presented with AKI that was preceded by episodes of ongoing diarrhea ranging from 10 to 90 days. All patients were on vitamin C and/or multivitamin supplementation. Two of the three patients needed long-term renal replacement therapy with the third patient recovering his kidney function after 2 months. The risks versus benefits of vitamin C supplementation in renal transplant patients should be carefully evaluated especially in the setting of gastrointestinal dysfunction.
Details
- Title: Subtitle
- Secondary oxalosis induced acute kidney injury in allograft kidneys
- Creators
- Manish Suneja - University of IowaAvinash B. Kumar - Vanderbilt University Medical Center
- Resource Type
- Journal article
- Publication Details
- Clinical kidney journal, Vol.6(1), pp.84-86
- Publisher
- Oxford University Press
- DOI
- 10.1093/ckj/sfs167
- PMID
- 27818757
- PMCID
- PMC5094400
- ISSN
- 2048-8505
- eISSN
- 2048-8513
- Language
- English
- Date published
- 01/04/2013
- Academic Unit
- Nephrology; Internal Medicine
- Record Identifier
- 9984359590402771
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