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Selective [2+2+2] Cycloaddition of Nickel-Benzyne and an Asymmetric 1,3-Diyne: An Iterative Route to Substituted [n]Acenes
Journal article   Peer reviewed

Selective [2+2+2] Cycloaddition of Nickel-Benzyne and an Asymmetric 1,3-Diyne: An Iterative Route to Substituted [n]Acenes

Kimberly R. Deaton, Christopher S. Strouse and Mary S. Gin
Synthesis (Stuttgart), Vol.2004(18), pp.3084-3088
12/17/2004
DOI: 10.1055/s-2004-834894

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Abstract

Abstract A new iterative route to substituted acenes is reported that centers on regioselective cycloaddition of a nickel-benzyne and 1-trimethylsilyl-1,3-pentadiyne. The five-step sequence installs two fused aromatic rings and two methyl substituents onto the backbone in 27% overall yield.
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