Journal article
Self-reported mechanical problems during condom use and semen exposure : Comparison of two randomized trials in the United States of America and Brazil
Sexually transmitted diseases, Vol.34(8), pp.557-562
08/2007
DOI: 10.1097/01.olq.0000258487.38309.b9
PMID: 17417133
Abstract
Objectives/Goal:
To compare self-reported condom use problems and objectively determined semen exposure in 2 populations.
Study Design:
Two randomized crossover trials in the United States and Brazil compared the failure rates of the female condom (FC) and male condom (MC). Participants used both condom types, completed condom-specific questionnaires to report problems, and collected precoital and postcoital samples of vaginal fluid. Prostate-specific antigen (PSA) was detected by immunoassay.
Results:
Problems with condom use were reported less frequently in the Brazilian study (rate difference: FC = 24%, P <0.0001, MC = 5%, P = 0.003). By contrast, the PSA detection rates were similar for both the FC and the MC (rate difference: FC = 2%, MC = 1%, not significant). These results suggest that the PSA detection rate was similar in the 2 study groups and that self-reported problems may be a less reliable measure of condom failure.
Conclusions:
Use of biomarkers of condom failure like PSA may help to strengthen the validity of studies promoting behavior change for the prevention of sexually transmitted diseases.
Details
- Title: Subtitle
- Self-reported mechanical problems during condom use and semen exposure : Comparison of two randomized trials in the United States of America and Brazil
- Creators
- Michael P Chen - Centers for Disease Control and PreventionMaurizio Macaluso - Centers for Disease Control and PreventionRichard Blackwell - University of Alabama at BirminghamLoren Galvao - Center for Urban Population HealthAndrzej Kulczycki - University of Alabama at BirminghamJuan Diaz - Population Council, Campinas, BrazilDenise J Jamieson - Centers for Disease Control and PreventionAnn Duerr - HIV Vaccine Trials Network, Seattle, Washington, United States
- Resource Type
- Journal article
- Publication Details
- Sexually transmitted diseases, Vol.34(8), pp.557-562
- Publisher
- Lippincott
- DOI
- 10.1097/01.olq.0000258487.38309.b9
- PMID
- 17417133
- ISSN
- 0148-5717
- eISSN
- 1537-4521
- Language
- English
- Date published
- 08/2007
- Academic Unit
- Obstetrics and Gynecology; VPMA - Administration
- Record Identifier
- 9984446454202771
Metrics
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