Journal article
Sellar Reconstruction With a Bioabsorbable Plate After Endoscopic Transsphenoidal Pituitary Adenoma Resection: Safe and Efficacious
Annals of otology, rhinology & laryngology, Vol.133(5), pp.490-494
05/2024
DOI: 10.1177/00034894241233870
PMID: 38372259
Abstract
To report outcomes of a large cohort of patients who underwent endoscopic endonasal transsphenoidal surgery (EETS) for resection of a pituitary adenoma with subsequent Resorb-X plate (RXP) sellar reconstruction.
A retrospective review of 620 EETS operations performed at a single academic center between 2005 and 2020 was conducted.
A total of 215 EETS operations of 208 patients were identified between 2012 and 2020 who underwent reconstruction with the RXP after EETS for pituitary tumor resection with a final pathologic diagnosis of pituitary adenoma. Analysis of pooled data revealed a mean preoperative tumor volume of 6.8 cm
(range: 0.038-51.03 cm
). Postoperative cerebrospinal fluid leak occurred in 2 patients (0.93%). Postoperative meningitis occurred in 1 patient (0.47%). There were no cases of RXP extrusion.
The rate of postoperative CSF leak and meningitis after use of the RXP for sellar reconstruction compares favorably to other methods, including use of autologous grafts and flaps. Use of RXP during EETS is a safe and efficacious method of sellar reconstruction and may obviate the need for autologous tissue reconstruction after pituitary adenoma resection.
Details
- Title: Subtitle
- Sellar Reconstruction With a Bioabsorbable Plate After Endoscopic Transsphenoidal Pituitary Adenoma Resection: Safe and Efficacious
- Creators
- Ryan Kendall Thorpe - University of IowaMark C Dougherty - University of IowaJarrett E Walsh - University of IowaScott M Graham - University of IowaJeremy D W Greenlee - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Annals of otology, rhinology & laryngology, Vol.133(5), pp.490-494
- DOI
- 10.1177/00034894241233870
- PMID
- 38372259
- eISSN
- 1943-572X
- Grant note
- DOI: 10.13039/100000055, name: National Institute on Deafness and Other Communication Disorders, award: 5T32DC000040
- Language
- English
- Electronic publication date
- 02/19/2024
- Date published
- 05/2024
- Academic Unit
- Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984560488502771
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