Sensitivity and Specificity of the Humphrey Matrix to Detect Homonymous Hemianopias

Parisa Taravati; Kimberly R Woodward; John L Keltner; Chris A Johnson; Daniel Redline; James Carolan; Charles Q Huang; Michael Wall

doi:10.1167/iovs.07-0248

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Sensitivity and Specificity of the Humphrey Matrix to Detect Homonymous Hemianopias

Journal article

Peer reviewed

Sensitivity and Specificity of the Humphrey Matrix to Detect Homonymous Hemianopias

Parisa Taravati, Kimberly R Woodward, John L Keltner, Chris A Johnson, Daniel Redline, James Carolan, Charles Q Huang and Michael Wall

Investigative ophthalmology & visual science, Vol.49(3), pp.924-928

2008

DOI: 10.1167/iovs.07-0248

PMID: 18326713

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Abstract

Purpose: To compare the sensitivity and specificity of the Humphrey Matrix frequency-doubling perimeter (Carl Zeiss Meditec, Inc., Dublin, CA) to that of standard automated perimetry (SAP) in detecting homonymous hemianopic visual field defects. Methods: Thirty-three patients with homonymous hemianopias and 50 normal subjects were tested with SAP with the Humphrey Visual Field Analyzer (SITA standard program 24-2) and Humphrey Matrix frequency-doubling perimetry, program 24-2 (Matrix) on the same day. Patients with hemianopias had lesions of the retrochiasmal visual system that were documented by magnetic resonance imaging or by computed tomography. To be classified as a hemianopic visual field defect, the abnormal test location had to be homonymous, respect the vertical meridian, and have no additional scattered abnormal points that obscured the hemianopic pattern. The sensitivity and specificity of SAP and Matrix in detecting hemianopic defects were calculated. The chi(2) test was used to test for differences between groups. Results: The sensitivity for hemianopic defects by total deviation probability plots was 75% for SAP and 59% for Matrix (not statistically significant, P = 0.29). The sensitivity of hemianopic defects by pattern deviation probability plots was 88% for SAP and 69% for Matrix (not statistically significant, P = 0.13). The specificity of total deviation probability plots was 84% for SAP and 86% for Matrix. The specificity of the pattern deviation probability plots was 68% for SAP and 74% for Matrix. Conclusions: Although there was no statistically significant difference between the Matrix and SAP in the detection of hemianopias, the sensitivity of SAP was higher, probably because of the obscuration of defects by scattered abnormal test locations with the Matrix.

Ophthalmology

Biological and medical sciences

Diseases of visual field, optic nerve, optic chiasma and optic tracts

Eye and associated structures. Visual pathways and centers. Vision

Fundamental and applied biological sciences. Psychology

Medical sciences

Vertebrates: nervous system and sense organs

Details

Title: Subtitle: Sensitivity and Specificity of the Humphrey Matrix to Detect Homonymous Hemianopias
Creators: Parisa Taravati - University of Iowa
Kimberly R Woodward - University of Iowa
John L Keltner - University of California, Davis
Chris A Johnson - Legacy Clinical Research and Technology Center
Daniel Redline - University of California, Davis
James Carolan - University of California, Davis
Charles Q Huang - University of California, Davis
Michael Wall - University of Iowa
Resource Type: Journal article
Publication Details: Investigative ophthalmology & visual science, Vol.49(3), pp.924-928
DOI: 10.1167/iovs.07-0248
PMID: 18326713
NLM abbreviation: Invest Ophthalmol Vis Sci
ISSN: 0146-0404
eISSN: 1552-5783
Publisher: Association for Research in Vision and Ophtalmology
Language: English
Date published: 2008
Academic Unit: Neurology; Ophthalmology and Visual Sciences
Record Identifier: 9984187133002771

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