Sensory-motor networks involved in speech production and motor control: an fMRI study

Roozbeh Behroozmand; Rachel Shebek; Daniel R Hansen; Hiroyuki Oya; Donald A Robin; Matthew A Howard III; Jeremy D W Greenlee

doi:10.1016/j.neuroimage.2015.01.040

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Sensory-motor networks involved in speech production and motor control: an fMRI study

Journal article

Peer reviewed

Sensory-motor networks involved in speech production and motor control: an fMRI study

Roozbeh Behroozmand, Rachel Shebek, Daniel R Hansen, Hiroyuki Oya, Donald A Robin, Matthew A Howard III and Jeremy D W Greenlee

NeuroImage (Orlando, Fla.), Vol.109, pp.418-428

04/01/2015

DOI: 10.1016/j.neuroimage.2015.01.040

PMCID: PMC4339397

PMID: 25623499

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https://www.ncbi.nlm.nih.gov/pmc/articles/4339397View

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Abstract

Speaking is one of the most complex motor behaviors developed to facilitate human communication. The underlying neural mechanisms of speech involve sensory-motor interactions that incorporate feedback information for online monitoring and control of produced speech sounds. In the present study, we adopted an auditory feedback pitch perturbation paradigm and combined it with functional magnetic resonance imaging (fMRI) recordings in order to identify brain areas involved in speech production and motor control. Subjects underwent fMRI scanning while they produced a steady vowel sound /a/ (speaking) or listened to the playback of their own vowel production (playback). During each condition, the auditory feedback from vowel production was either normal (no perturbation) or perturbed by an upward (+600 cents) pitch-shift stimulus randomly. Analysis of BOLD responses during speaking (with and without shift) vs. rest revealed activation of a complex network including bilateral superior temporal gyrus (STG), Heschl's gyrus, precentral gyrus, supplementary motor area (SMA), Rolandic operculum, postcentral gyrus and right inferior frontal gyrus (IFG). Performance correlation analysis showed that the subjects produced compensatory vocal responses that significantly correlated with BOLD response increases in bilateral STG and left precentral gyrus. However, during playback, the activation network was limited to cortical auditory areas including bilateral STG and Heschl's gyrus. Moreover, the contrast between speaking vs. playback highlighted a distinct functional network that included bilateral precentral gyrus, SMA, IFG, postcentral gyrus and insula. These findings suggest that speech motor control involves feedback error detection in sensory (e.g. auditory) cortices that subsequently activate motor-related areas for the adjustment of speech parameters during speaking.

Magnetic Resonance Imaging

Pitch Perception - physiology

Acoustic Stimulation

Humans

Male

Sensorimotor Cortex - physiology

Auditory Perception - physiology

Motor Activity

Brain - physiology

Speech Perception - physiology

Speech - physiology

Nerve Net

Brain Mapping

Phonetics

Adult

Female

Feedback, Sensory

Details

Title: Subtitle: Sensory-motor networks involved in speech production and motor control: an fMRI study
Creators: Roozbeh Behroozmand - Human Brain Research Lab, Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, United States; Speech Neuroscience Lab, Department of Communication Sciences and Disorders, University of South Carolina, Columbia, SC 29208, United States. Electronic address: r-behroozmand@sc.edu
Rachel Shebek - Human Brain Research Lab, Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, United States
Daniel R Hansen - Human Brain Research Lab, Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, United States
Hiroyuki Oya - Human Brain Research Lab, Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, United States
Donald A Robin - Research Imaging Institute, Departments of Neurology, Radiology and Biomedical Engineering, University of Texas Health Science Center San Antonio, San Antonio, TX 78229, United States
Matthew A Howard III - Human Brain Research Lab, Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, United States
Jeremy D W Greenlee - Human Brain Research Lab, Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, United States
Resource Type: Journal article
Publication Details: NeuroImage (Orlando, Fla.), Vol.109, pp.418-428
DOI: 10.1016/j.neuroimage.2015.01.040
PMID: 25623499
PMCID: PMC4339397
NLM abbreviation: Neuroimage
ISSN: 1053-8119
eISSN: 1095-9572
Publisher: United States
Grant note: R01 DC004290 / NIDCD NIH HHS R01DC04290 / NIDCD NIH HHS K23 DC009589 / NIDCD NIH HHS K23DC009589 / NIDCD NIH HHS
Language: English
Date published: 04/01/2015
Academic Unit: Neurology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
Record Identifier: 9984018741202771

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