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Serial cytogenetic analysis of a recurrent malignant melanoma
Journal article

Serial cytogenetic analysis of a recurrent malignant melanoma

Hisako Ochi, Norio Wake, Uma Rao, Jin Takeuchi, Harry K. Slocum, Youcef M. Rustum, Constantine Karakousis and Avery A. Sandberg
Cancer genetics and cytogenetics, Vol.11(2), pp.175-183
1984
DOI: 10.1016/0165-4608(84)90112-2
PMID: 6692338

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Abstract

A metastatic malignant melanoma in a 54-yr-old white female was examined cytogenetically on three different occasions. We found two different clones, one hypodiploid and another hypertriploid; however, both clones had the same markers [i.e., der(6),t(6;17), and der(17),t(1;17)]. Detailed analysis of the histopathology and clinical course suggests that these two different clones reflected different morphology and results of therapy.

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