Journal article
Serotonin: The Anti-SuddenDeathAmine?
Epilepsy currents, Vol.13(5), pp.241-244
2013
DOI: 10.5698/1535-7597-13.5.241
PMCID: PMC3854735
PMID: 24348119
Abstract
Sudden unexpected death in epilepsy (SUDEP) is an exceptionally difficult condition to study in humans. Therefore, translational research in animal models has been very important in defining pathophysiological mechanisms of death and identifying potential treatments. These models are helping define whether the primary mechanism of death is cardiac or respiratory. They have also identified a link to the serotonergic system of the brainstem; this, in turn, led to recognition that SUDEP and sudden infant death syndrome (SIDS) may share a common final pathway in the sequence of events that lead to death.
Details
- Title: Subtitle
- Serotonin: The Anti-SuddenDeathAmine?
- Creators
- George B Richerson - Departments of Neurology and Molecular Physiology & Biophysics, University of Iowa, Veteran's Affairs Medical Center, Iowa City, IA
- Resource Type
- Journal article
- Publication Details
- Epilepsy currents, Vol.13(5), pp.241-244
- DOI
- 10.5698/1535-7597-13.5.241
- PMID
- 24348119
- PMCID
- PMC3854735
- NLM abbreviation
- Epilepsy Curr
- ISSN
- 1535-7597
- eISSN
- 1535-7511
- Publisher
- American Epilepsy Society
- Alternative title
- Serotonin & SUDEP
- Language
- English
- Date published
- 2013
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020792702771
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