Journal article
Serum albumin in older persons: Relationship with age and health status
Journal of clinical epidemiology, Vol.45(3), pp.213-221
1992
DOI: 10.1016/0895-4356(92)90081-W
PMID: 1569418
Abstract
We analyzed data from 4115 persons aged 71 years and older who had blood drawn at a home visit in three communities to examine the cross-sectional distribution of serum albumin and correlates of hypoalbuminemia. Mean albumin was lower among older persons, from 41.6 g/l in men aged 71–74 years to 38.5 g/l in men 90 years or older, and from 41.1 g/1 to 38.9 g/1 in women of the same ages, respectively. Hypoalbuminemia (albumin < 35 g/1) was observed in 3.1 % of subjects. Hypoalbuminemia and lower serum albumin were independently associated with anemia, recent diagnosis of cancer, two or more limitations in activities of daily living, residence in a nursing home, heavy cigarette smoking ( > 1 pack/day), and older age. A 10-year age increment was associated with 0.8 g/l lower serum albumin and odds ratio of 1.56 (95% CI 1.14, 2.13) for hypoalbuminemia after adjusting for demographic factors and health status. Characteristics associated with serum albumin may confound the reported relationship between serum albumin and mortality.
Details
- Title: Subtitle
- Serum albumin in older persons: Relationship with age and health status
- Creators
- Marcel E. Salive - National Institute on AgingJoan Cornoni-Huntley - National Institute on AgingCaroline L. Phillips - National Institute on AgingJack M. Guralnik - National Institute on AgingHarvey J. Cohen - Duke UniversityAdrian M. Ostfeld - Yale UniversityRobert B. Wallace - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of clinical epidemiology, Vol.45(3), pp.213-221
- DOI
- 10.1016/0895-4356(92)90081-W
- PMID
- 1569418
- NLM abbreviation
- J Clin Epidemiol
- ISSN
- 0895-4356
- eISSN
- 1878-5921
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1992
- Academic Unit
- Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984363615202771
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