Journal article
Sex Differences in Peripheral Augmentation Index and Arterial Reservoir Pressure during Upper Limb Postural Shifts
Physiology journal, Vol.2014, pp.1-10
01/05/2014
DOI: 10.1155/2014/971906
Abstract
We examined the peripheral hemodynamic response to passive arm postural changes in young men and women. Radial artery pulse waveforms were captured using applanation tonometry in 20 men (age 27 ± 2 yrs, BMI 25 ± 1 kg/m
2
) and 20 women (age 27 ± 2 yrs, BMI 23±1 kg/m
2
). Arm position was maintained at either heart level or supported 14 cm above/below heart level in a randomized fashion. Systolic augmentation index (sAIx) and diastolic augmentation index (dAIx) were used as estimates of pressure from wave reflections arriving in systole and diastole, respectively. A novel reservoir-wave separation technique was used to obtain arterial reservoir pressure (pressure generated by arterial capacitance). Women showed a significant reduction in radial diastolic pressure-time integral (DPTI) (
P
<
0.05
) and reservoir pressure (
P
<
0.05
), with no change in peripheral sAIx (
P
>
0.05
) or dAIx (
P
>
0.05
) when moving the arm from below to above heart level. Conversely, men showed an attenuated change in radial DPTI (
P
>
0.05
) concomitant with significant increases in reservoir pressure (
P
<
0.05
), sAIx (
P
<
0.05
), and dAIx (
P
<
0.05
). Gravity-mediated changes in regional hemodynamics produced by passive arm postural shifts are sex specific. Men demonstrate less change in regional diastolic pressure concomitant with increased augmentation index and arterial reservoir pressure.
Details
- Title: Subtitle
- Sex Differences in Peripheral Augmentation Index and Arterial Reservoir Pressure during Upper Limb Postural Shifts
- Creators
- Kevin S. Heffernan - Syracuse UniversityAri G. Kasprowicz - Syracuse UniversityBrendan J. Tarzia - Syracuse UniversityJustin E. Davies - Imperial College Healthcare NHS TrustDarren P. Casey - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Physiology journal, Vol.2014, pp.1-10
- DOI
- 10.1155/2014/971906
- ISSN
- 2314-4300
- eISSN
- 2314-4319
- Grant note
- name: Joan N. Burstyn Endowed Fund
- Language
- English
- Date published
- 01/05/2014
- Academic Unit
- Physical Therapy and Rehabilitation Science; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984294931002771
Metrics
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