Sexual dysfunction in women with type 1 diabetes: long-term findings from the DCCT/ EDIC study cohort

Paul Enzlin; Raymond Rosen; Markus Wiegel; Jeanette Brown; Hunter Wessells; Patricia Gatcomb; Brandy Rutledge; Ka-Ling Chan; Patricia A Cleary; Diabetes Control and Complications Trial (DCCT)/ Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group

doi:10.2337/dc08-1164

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Sexual dysfunction in women with type 1 diabetes: long-term findings from the DCCT/ EDIC study cohort

Journal article

Open access

Peer reviewed

Sexual dysfunction in women with type 1 diabetes: long-term findings from the DCCT/ EDIC study cohort

Paul Enzlin, Raymond Rosen, Markus Wiegel, Jeanette Brown, Hunter Wessells, Patricia Gatcomb, Brandy Rutledge, Ka-Ling Chan, Patricia A Cleary and Diabetes Control and Complications Trial (DCCT)/ Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group

Diabetes care, Vol.32(5), pp.780-785

05/2009

DOI: 10.2337/dc08-1164

PMID: 19407075

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Abstract

This study aimed to investigate the prevalence and risk factors associated with sexual dysfunction in a well-characterized cohort of women with type 1 diabetes. The study was conducted in women enrolled in the long-term Epidemiology of Diabetes Interventions and Complications (EDIC) study, a North American study of men and women with type 1 diabetes. At year 10 of the EDIC study, 652 female participants were invited to complete a validated self-report measure of sexual function, standardized history and physical examinations, laboratory testing, and mood assessment. Of the sexually active women with type 1 diabetes in the EDIC study, 35% met criteria for female sexual dysfunction (FSD). Women with FSD reported loss of libido (57%); problems with orgasm (51%), lubrication (47%), and arousal (38%); and pain (21%). Univariate analyses revealed a positive association between FSD and age (P = 0.0041), marital status (P = 0.0016), menopausal status (P = 0.0019), microvasculopathy (P = 0.0092), and depression (P = 0.0022). However, in a multivariate analysis, only depression (P = 0.004) and marital status (P = 0.003) were significant predictors of FSD. FSD is common in women with type 1 diabetes and affects all aspects of sexual function and satisfaction. Depression is the major predictor of sexual dysfunction in women with type 1 diabetes. These findings suggest that women with type 1 diabetes should be routinely queried about the presence of sexual dysfunction and possible co-association with depression.

Albuminuria - epidemiology

Multivariate Analysis

Sexual Dysfunctions, Psychological - epidemiology

Glycated Hemoglobin A - metabolism

Humans

Middle Aged

Libido

Male

Marital Status

Creatinine - metabolism

Diabetic Retinopathy - epidemiology

Smoking - epidemiology

Adult

Diabetic Angiopathies - epidemiology

Female

Diabetic Nephropathies - epidemiology

Hypertension - epidemiology

Diabetes Mellitus, Type 1 - psychology

Details

Title: Subtitle: Sexual dysfunction in women with type 1 diabetes: long-term findings from the DCCT/ EDIC study cohort
Creators: Paul Enzlin - Department of Psychiatry, Katholieke Universiteit Leuven & University Hospitals Gasthuisberg, Leuven, Belgium. paul.enzlin@uz.kuleuven.ac.be
Raymond Rosen
Markus Wiegel
Jeanette Brown
Hunter Wessells
Patricia Gatcomb
Brandy Rutledge
Ka-Ling Chan
Patricia A Cleary
Diabetes Control and Complications Trial (DCCT)/ Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group
Contributors: H Culver Boldt (Contributor) - University of Iowa, Ophthalmology and Visual Sciences
Resource Type: Journal article
Publication Details: Diabetes care, Vol.32(5), pp.780-785
DOI: 10.2337/dc08-1164
PMID: 19407075
NLM abbreviation: Diabetes Care
ISSN: 0149-5992
eISSN: 1935-5548
Publisher: United States
Language: English
Date published: 05/2009
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9983980049702771

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