Journal article
Shedding light on inflammatory pseudotumor in children: spotlight on inflammatory myofibroblastic tumor
Pediatric radiology, Vol.45(12), pp.1738-1752
11/2015
DOI: 10.1007/s00247-015-3360-6
PMID: 25964134
Abstract
Inflammatory pseudotumor is a generic term used to designate a heterogeneous group of inflammatory mass-forming lesions histologically characterized by myofibroblastic proliferation with chronic inflammatory infiltrate. Inflammatory pseudotumor is multifactorial in etiology and generally benign, but it is often mistaken for malignancy given its aggressive appearance. It can occur throughout the body and is seen in all age groups. Inflammatory pseudotumor has been described in the literature by many organ-specific names, resulting in confusion. Recently within this generic category of inflammatory pseudotumor, inflammatory myofibroblastic tumor has emerged as a distinct entity and is now recognized as a fibroblastic/myofibroblastic neoplasm with intermediate biological potential and occurring mostly in children. We present interesting pediatric cases of inflammatory myofibroblastic tumors given this entity's tendency to occur in children. Familiarity and knowledge of the imaging features of inflammatory pseudotumor can help in making an accurate diagnosis, thereby avoiding unnecessary radical surgery.
Details
- Title: Subtitle
- Shedding light on inflammatory pseudotumor in children: spotlight on inflammatory myofibroblastic tumor
- Creators
- Lillian M Lai - Department of Radiology, Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Room 3970 JPP, Iowa City, IA, 52242, USA. lillian.lai@gmail.comM Beth McCarville - Department of Radiology, St. Jude Children's Research Hospital, Memphis, TN, USAPatricia Kirby - Department of Pathology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USASimon C S Kao - Department of Radiology, Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Room 3970 JPP, Iowa City, IA, 52242, USAToshio Moritani - Department of Radiology, Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Room 3970 JPP, Iowa City, IA, 52242, USAEve Clark - Department of Radiology, Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Room 3970 JPP, Iowa City, IA, 52242, USAKousei Ishigami - Department of Radiology, Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Room 3970 JPP, Iowa City, IA, 52242, USAArmita Bahrami - Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USAYutaka Sato - Department of Radiology, Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Room 3970 JPP, Iowa City, IA, 52242, USA
- Resource Type
- Journal article
- Publication Details
- Pediatric radiology, Vol.45(12), pp.1738-1752
- Publisher
- Germany
- DOI
- 10.1007/s00247-015-3360-6
- PMID
- 25964134
- ISSN
- 0301-0449
- eISSN
- 1432-1998
- Language
- English
- Date published
- 11/2015
- Academic Unit
- Radiology; Stead Family Department of Pediatrics; Pathology
- Record Identifier
- 9984051775502771
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