Short Synthetic Oligonucleotide Repeats Detect Human Genomic Variation

Eric J. Devor; A. K. Burgess

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Short Synthetic Oligonucleotide Repeats Detect Human Genomic Variation

Journal article

Peer reviewed

Short Synthetic Oligonucleotide Repeats Detect Human Genomic Variation

Eric J. Devor and A. K. Burgess

Human Biology, Vol.61(4), pp.533-541

08/01/1989

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Abstract

We used synthetic oligonucleotide DNA probes specific for the four-base repetitive core sequences (GACA)n and (AGGC)n to examine human genomic variation. The results of hybridizing these oligonucleotides to human genomic digests indicate that they are useful and accessible markers for ubiquitously repeated regions of DNA in the human genome. Furthermore, these sequences appear to be highly conserved in eukaryotic genomes, but their function remains largely unknown.

Obstetrics and Gynecology

Details

Title: Subtitle: Short Synthetic Oligonucleotide Repeats Detect Human Genomic Variation
Creators: Eric J. Devor - University of Iowa
A. K. Burgess
Resource Type: Journal article
Publication Details: Human Biology, Vol.61(4), pp.533-541
ISSN: 0018-7143
Language: English
Date published: 08/01/1989
Academic Unit: Obstetrics and Gynecology
Record Identifier: 9983557124302771

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