Silicon Nanowires and Their Impact on Cancer Detection and Monitoring

Rasheid Smith; Sean M Geary; Aliasger K Salem

doi:10.1021/acsanm.0c01572

Back

Silicon Nanowires and Their Impact on Cancer Detection and Monitoring

Journal article

Peer reviewed

Silicon Nanowires and Their Impact on Cancer Detection and Monitoring

Rasheid Smith, Sean M Geary and Aliasger K Salem

ACS applied nano materials, Vol.3(9), pp.8522-8536

09/25/2020

DOI: 10.1021/acsanm.0c01572

PMCID: PMC9891666

PMID: 36733606

Files and links (1)

url

https://www.ncbi.nlm.nih.gov/pmc/articles/9891666View

Open Access

Abstract

Since the inception of silicon nanowire (SiNW)-based biosensors in 2001, SiNWs have been employed in various detection schemes and have routinely demonstrated the capability for label-free, real-time, sub-femtomolar detection of both protein and nucleic acid analytes. This has allowed SiNW-based biosensors to integrate into the field of cancer detection and cancer monitoring and thus has the potential to be a paradigm shift in how cancer biomarkers are detected and monitored. Combining this with several promising fields such as liquid biopsies and targeted oncology, SiNW based biosensors represent an opportunity for cancer monitoring and treatment to be a more dynamic process. Such advances can provide clinicians with more information in a shorter time frame on the molecular landscape of cancer patients, which can better inform cancer treatment guidelines.

Details

Title: Subtitle: Silicon Nanowires and Their Impact on Cancer Detection and Monitoring
Creators: Rasheid Smith - Division of Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, United States
Sean M Geary - Division of Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, United States
Aliasger K Salem - Division of Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, United States
Resource Type: Journal article
Publication Details: ACS applied nano materials, Vol.3(9), pp.8522-8536
DOI: 10.1021/acsanm.0c01572
PMID: 36733606
PMCID: PMC9891666
NLM abbreviation: ACS Appl Nano Mater
ISSN: 2574-0970
eISSN: 2574-0970
Grant note: DOI: 10.13039/100000002, name: National Institutes for Health, award: P30 CA086862
Language: English
Date published: 09/25/2020
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Pharmaceutical Sciences and Experimental Therapeutics; Craniofacial Anomalies Research Center; Dental Research; Chemical and Biochemical Engineering
Record Identifier: 9984216588002771

Metrics

11 Record Views

32 Times Cited - Web of Science