Journal article
Simulation of exchanges of multiple gases in bubbles in the body
Respiration physiology, Vol.95(2), pp.131-145
02/01/1994
DOI: 10.1016/0034-5687(94)90111-2
PMID: 8191036
Abstract
This communication introduces a system of equations, for numerical solution, which simulates the generation, growth, and decay of bubbles. The system is an advance over previous works because it allows for simultaneous diffusion of any number of gases. Our purpose for developing the system is to gain insight into the bubbles that occur in the body in decompression sickness (DCS). We validate the calculation system by matching observed data of DCS bubbles and of large subcutaneous gas pockets in rats. We demonstrate how a temporary supersaturation and bubble formation can occur without change of ambient pressure when there is a change in the inert gas being breathed. With exposures to hypobaric environments, such as when astronauts work in space, simulations show that O
2, CO
2, and water vapor add appreciably to volume of bubbles and affect the diffusion of inert gas.
Details
- Title: Subtitle
- Simulation of exchanges of multiple gases in bubbles in the body
- Creators
- Mark E. Burkard - University at Buffalo, State University of New YorkHugh D. Van Liew
- Resource Type
- Journal article
- Publication Details
- Respiration physiology, Vol.95(2), pp.131-145
- Publisher
- Elsevier B.V
- DOI
- 10.1016/0034-5687(94)90111-2
- PMID
- 8191036
- ISSN
- 0034-5687
- Number of pages
- 15
- Language
- English
- Date published
- 02/01/1994
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984700655602771
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