Journal article
Simulation of pulmonary air flow with a subject-specific boundary condition
Journal of biomechanics, Vol.43(11), pp.2159-2163
2010
DOI: 10.1016/j.jbiomech.2010.03.048
PMCID: PMC3034656
PMID: 20483412
Abstract
We present a novel image-based technique to estimate a subject-specific boundary condition (BC) for computational fluid dynamics (CFD) simulation of pulmonary air flow. The information of regional ventilation for an individual is derived by registering two computed tomography (CT) lung datasets and then passed to the CT-resolved airways as the flow BC. The CFD simulations show that the proposed method predicts lobar volume changes consistent with direct image-measured metrics, whereas the other two traditional BCs (uniform velocity or uniform pressure) yield lobar volume changes and regional pressure differences inconsistent with observed physiology.
Details
- Title: Subtitle
- Simulation of pulmonary air flow with a subject-specific boundary condition
- Creators
- Youbing Yin - Department of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, Iowa, USAJiwoong Choi - Department of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, Iowa, USAEric A Hoffman - Department of Radiology, The University of Iowa, Iowa City, Iowa, USAMerryn H Tawhai - Auckland Bioengineering Institute, The University of Auckland, Auckland, New ZealandChing-Long Lin - Department of Mechanical and Industrial Engineering, The University of Iowa, Iowa City, Iowa, USA
- Resource Type
- Journal article
- Publication Details
- Journal of biomechanics, Vol.43(11), pp.2159-2163
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.jbiomech.2010.03.048
- PMID
- 20483412
- PMCID
- PMC3034656
- ISSN
- 0021-9290
- eISSN
- 1873-2380
- Language
- English
- Date published
- 2010
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Mechanical Engineering; Internal Medicine
- Record Identifier
- 9984051898802771
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