Journal article
Skin preparation for prevention of peripheral blood culture contamination in children
Pediatrics international, Vol.61(7), pp.647-651
07/01/2019
DOI: 10.1111/ped.13906
PMID: 31172642
Abstract
Background
In Japan, blood cultures for children are performed by pediatric residents, and povidone-iodine (PI) is the recommended solution for skin preparation. Given that PI needs to be applied for 1.5–2 min before venipuncture, skin preparation may be suboptimal if this is not followed. In this study, we investigated the blood culture contamination rate after skin preparation with only 70% isopropyl alcohol (IPA) or IPA plus PI.
Methods
We performed a retrospective study of patients aged ≤6 years who provided blood cultures in the emergency department or pediatric ward. Patients with indwelling central venous catheter were excluded. We evaluated the impact of changing the method of skin preparation, comparing the traditional method using IPA plus PI between 2008 and 2010 (IPA + PI group) with the simplified method using only IPA between 2015 and 2017 (IPA group).
Results
A total of 5,365 blood culture samples were eligible for this study. Of these, 171 (3.2%) had an organism identified in blood culture. Of the blood culture-positive samples, 68 (1.3%) were true positive and 103 (1.9%) were contaminated. Thirty-eight (1.6%) of 2,407 cultures in the IPA group were contaminated, whereas 65 (2.2%) of 2,958 cultures in the IPA + PI group were contaminated (OR, 0.72; 95%CI: 0.48–1.07; P = 0.1). Coagulase-negative Staphylococcus grew significantly less in the IPA group (1.7% vs 1.0%, P = 0.02).
Conclusions
A single application of 70% IPA may be the optimal skin preparation method for obtaining peripheral blood cultures from children in Japan.
Details
- Title: Subtitle
- Skin preparation for prevention of peripheral blood culture contamination in children
- Creators
- Toshifumi Yodoshi - Cincinnati Children's Hospital Medical CenterShinichiro Ueda - University of the RyukyusRan D. Goldman - University of British Columbia
- Resource Type
- Journal article
- Publication Details
- Pediatrics international, Vol.61(7), pp.647-651
- DOI
- 10.1111/ped.13906
- PMID
- 31172642
- ISSN
- 1328-8067
- eISSN
- 1442-200X
- Number of pages
- 5
- Grant note
- School of Medicine, Emory University (http://data.elsevier.com/vocabulary/SciValFunders/100007623)
- Language
- English
- Date published
- 07/01/2019
- Academic Unit
- Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9985214173602771
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