Journal article
Sleep Duration, Sleep Apnea, and Gray Matter Volume
Journal of Geriatric Psychiatry and Neurology, Vol.35(1), pp.47-56
2022
DOI: 10.1177/0891988720988918
Abstract
This study aimed to evaluate the effect of sleep duration on brain structures in the presence versus absence of sleep apnea in middle-aged and older individuals. The study investigated a population-based sample of 2,560 individuals, aged 49-80 years. The presence of sleep apnea and self-reported sleep duration were examined in relation to gray matter volume (GMV) in total and lobar brain regions. We identified ranges of sleep duration associated with maximal GMV using quadratic regression and bootstrap sampling. A significant quadratic association between sleep duration and GMV was observed in total and lobar brain regions of men with sleep apnea. In the fully adjusted model, optimal sleep durations associated with peak GMV between brain regions ranged from 6.7 to 7.0 hours. Shorter and longer sleep durations were associated with lower GMV in total and 4 sub-regions of the brain in men with sleep apnea.
Details
- Title: Subtitle
- Sleep Duration, Sleep Apnea, and Gray Matter Volume
- Creators
- REY KimR D Abbott - Korea UniversityS Kim - Korea UniversityR J Thomas - Seoul National University Bundang HospitalC H Yun - Harvard UniversityH Kim - Boston UniversityH Johnson - University of IowaC Shin - Korea University
- Resource Type
- Journal article
- Publication Details
- Journal of Geriatric Psychiatry and Neurology, Vol.35(1), pp.47-56
- DOI
- 10.1177/0891988720988918
- ISSN
- 1552-5708
- Grant note
- DOI: 10.13039/501100003669, name: Korea Centers for Disease Control & Prevention, award: 2011-E71004-00
- Language
- English
- Date published
- 2022
- Academic Unit
- Psychiatry; The Iowa Institute for Biomedical Imaging; Electrical and Computer Engineering; Roy J. Carver Department of Biomedical Engineering; The Iowa Initiative for Artificial Intelligence; Iowa Informatics Initiative
- Record Identifier
- 9984231911302771
Metrics
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