Sleep apnea and intracranial hypertension in men

Andrew G Lee; Karl Golnik; Randy Kardon; Michael Wall; Eric Eggenberger; Sunita Yedavally

doi:10.1016/s0161-6420(01)00987-3

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Sleep apnea and intracranial hypertension in men

Journal article

Peer reviewed

Sleep apnea and intracranial hypertension in men

Andrew G Lee, Karl Golnik, Randy Kardon, Michael Wall, Eric Eggenberger and Sunita Yedavally

Ophthalmology (Rochester, Minn.), Vol.109(3), pp.482-485

03/2002

DOI: 10.1016/s0161-6420(01)00987-3

PMID: 11874748

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Abstract

To investigate sleep apnea as an associated finding in idiopathic intracranial hypertension (IIH) in men. Multicenter, retrospective, noncomparative interventional case series. Retrospective review of all men with the diagnosis of IIH seen within the last 5 years at three tertiary care academic ophthalmologic institutions. Cases with sleep apnea (SA) and IIH were identified and reviewed. Thirty-two cases of IIH in men were reviewed. Six cases with SA met the modified Dandy criteria for the diagnosis of IIH. Of these six patients, one received acetazolamide alone, four received acetazolamide and continuous positive airway pressure (CPAP), and one was treated with CPAP alone. All patients had preserved central acuity (20/20 or better in both eyes), enlarged blind spots, and optic disc edema in both eyes. Five patients had normal visual fields after treatment, and one patient had residual visual field loss. Three patients had normal optic nerve examinations, with resolution of the optic disc edema at last follow-up. After resolution of the optic disc edema, these three patients were maintained on CPAP but discontinued acetazolamide. Two patients had persistent but improved papilledema and are under continued treatment with acetazolamide and CPAP. One patient had optic disc pallor in both eyes and is stable. SA was a common finding in men meeting the modified Dandy criteria for IIH in adults. Treatment of sleep apnea with nocturnal oxygenation may improve the signs and symptoms of IIH in affected men.

Pseudotumor Cerebri - therapy

Humans

Middle Aged

Pseudotumor Cerebri - diagnosis

Male

Visual Acuity

Positive-Pressure Respiration

Sleep Apnea Syndromes - complications

Intracranial Pressure

Sleep Apnea Syndromes - diagnosis

Visual Fields

Pseudotumor Cerebri - complications

Adult

Retrospective Studies

Acetazolamide - therapeutic use

Sleep Apnea Syndromes - therapy

Carbonic Anhydrase Inhibitors - therapeutic use

Papilledema - drug therapy

Details

Title: Subtitle: Sleep apnea and intracranial hypertension in men
Creators: Andrew G Lee - University of Iowa, Ophthalmology and Visual Sciences
Karl Golnik
Randy Kardon - University of Iowa, Ophthalmology and Visual Sciences
Michael Wall - University of Iowa, Ophthalmology and Visual Sciences
Eric Eggenberger
Sunita Yedavally
Resource Type: Journal article
Publication Details: Ophthalmology (Rochester, Minn.), Vol.109(3), pp.482-485
DOI: 10.1016/s0161-6420(01)00987-3
PMID: 11874748
NLM abbreviation: Ophthalmology
ISSN: 0161-6420
eISSN: 1549-4713
Publisher: United States
Language: English
Date published: 03/2002
Academic Unit: Neurology; Iowa Neuroscience Institute; Ophthalmology and Visual Sciences
Record Identifier: 9983980083402771

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