Journal article
Sleep disordered breathing and hypertension
Current opinion in pulmonary medicine, Vol.7(6), pp.386-390
11/2001
DOI: 10.1097/00063198-200111000-00004
PMID: 11706313
Abstract
Patients with sleep apnea may be at increased risk for cardiovascular disease. Recently, the link between hypertension and sleep apnea has been strengthened by findings of two large epidemiologic studies. Neurohumoral and hemodynamic responses to repetitive episodes of hypoxemia and apnea may offer a pathophysiologic basis for patients with sleep apnea having an increased risk for hypertension. Sympathetic, humoral, and cellular responses to sleep apnea over the long term may cause vascular dysfunction and consequent hypertension. These responses may be exacerbated by sleep deprivation, which occurs commonly in patients with sleep apnea because of poor sleep architecture. Patients with sleep apnea are often obese and may be predisposed to weight gain. Hence, obesity may further contribute to cardiovascular risk in this patient population. Alleviation of sleep disordered breathing may be accompanied by lower blood pressure in hypertensive patients with sleep apnea.
Details
- Title: Subtitle
- Sleep disordered breathing and hypertension
- Creators
- Herbert Berger - University of IowaVirend Somers - Cardiovascular MedicineBradley Phillips - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Current opinion in pulmonary medicine, Vol.7(6), pp.386-390
- Publisher
- Wolters Kluwer Health
- DOI
- 10.1097/00063198-200111000-00004
- PMID
- 11706313
- ISSN
- 1070-5287
- eISSN
- 1531-6971
- Language
- English
- Date published
- 11/2001
- Academic Unit
- Pulmonary, Critical Care, and Occupational Medicine; Internal Medicine
- Record Identifier
- 9984359576002771
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